Substance / Medication

Phenobarbital sodium

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Impact of Diagnostic Criteria on UTI Prevalence in Young Infants With Jaundice: A Meta-analysis.
Chang Pearl W, Schroeder Alan R, Lucas Brian P et al. · Hosp Pediatr · 2022
PMID: 35322269Meta-Analysis
The prognostic significance of postoperative hyperbilirubinemia in cardiac surgery: systematic review and meta-analysis.
Raveendran Dev, Penny-Dimri Jahan C, Segal Reny et al. · J Cardiothorac Surg · 2022
PMID: 35619178Meta-AnalysisFull text (PMC)
Ursodeoxycholic acid as adjuvant treatment to phototherapy for neonatal hyperbilirubinemia: a systematic review and meta-analysis.
Kuitunen Ilari, Kiviranta Panu, Sankilampi Ulla et al. · World J Pediatr · 2022
PMID: 35689782Meta-AnalysisFull text (PMC)
Role of ursodeoxycholic acid in neonatal indirect hyperbilirubinemia: a systematic review and meta-analysis of randomized controlled trials.
Lazarus Glen, Francie Jerrell, Roeslani Rosalina Dewi et al. · Ital J Pediatr · 2022
PMID: 36253867Meta-AnalysisFull text (PMC)
Universal screening for hyperbilirubinemia in term healthy newborns at discharge: A systematic review and meta-analysis.
Khurshid Faiza, Rao Suman Pn, Sauve Caroline et al. · J Glob Health · 2022
PMID: 36579719Meta-AnalysisFull text (PMC)
Fluid restriction in the management of transient tachypnea of the newborn.
Gupta Neeraj, Bruschettini Matteo, Chawla Deepak · Cochrane Database Syst Rev · 2021
PMID: 33599990Meta-AnalysisFull text (PMC)
Preparation andevaluation of thermosensitive and mucoadhesive hydrogels for intranasal delivery of phenobarbital sodium.
Alami-Milani Mitra, Salatin Sara, Rayeni Farzaneh Sharifi et al. · Ther Deliv · 2021
PMID: 34013779Other
Pharmacokinetics of Intravenous and Oral Phenobarbital Sodium in Healthy Goats.
Yates Liana M, Aleman Monica, Knych Heather K et al. · Front Vet Sci · 2020
PMID: 32154280OtherFull text (PMC)
DSPE-PEG-methotrexate nanoparticles encapsulating phenobarbital sodium kill cancer cells by inducing pyroptosis.
Yin Fengyue, Xu Xiao, Qi Julia et al. · J Mol Med (Berl) · 2024
PMID: 38047923Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Phenobarbital sodium (substance)
SNOMED CT
76898000
UMLS CUI
C0282303

Clinical Data

This intervention maps to 3 entities in the Healos knowledge graph.

3
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.