Substance / Medication

Potassium chloride

Overview

Active Ingredient
potassium chloride
RxNorm CUI
8591

Indications

Potassium chloride extended-release capsules are indicated for the treatment and prophylaxis of hypokalemia in adults and children with or without metabolic alkalosis, in patients for whom dietary management with potassium-rich foods or diuretic dose reduction is insufficient.

Labeler: A-S Medication SolutionsUpdated: 2026-02-23T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Potassium chloride extended-release capsules are contraindicated in patients on amiloride or triamterene.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Research Evidence

Published studies and systematic reviews

Sort:
Potassium Magnesium Citrate Is Superior to Potassium Chloride in Reversing Metabolic Side Effects of Chlorthalidone.
Vongpatanasin Wanpen, Giacona John M, Pittman Danielle et al. · Hypertension · 2023
PMID: 37846572RCTFull text (PMC)
A new and more effective feticide technique in late termination of pregnancy: potassium chloride injection into the interventricular septum of the fetal heart.
Süzen Çaypınar Sema, Oğlak Süleyman Cemil, Polat İbrahim et al. · Arch Gynecol Obstet · 2023
PMID: 36271257RCT
Preliminary evidence of effects of potassium chloride on a metabolomic path to diabetes and cardiovascular disease.
Chatterjee Ranee, Davenport Clemontina A, Kwee Lydia et al. · Metabolomics · 2020
PMID: 32556595RCTFull text (PMC)
Effects of potassium citrate or potassium chloride in patients with combined glucose intolerance: A placebo-controlled pilot study.
Conen Katrin, Scanni Roberto, Gombert Marie-Therese et al. · J Diabetes Complications · 2016
PMID: 27260862RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Potassium chloride (substance)
SNOMED CT
8631001
UMLS CUI
C0032825
RxNorm CUI
8591
Labeler
A-S Medication Solutions

Clinical Data

This intervention maps to 7 entities in the Healos knowledge graph.

1
Conditions
3
Biomarkers
2
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.