Substance / Medication

Pregabalin

Overview

Active Ingredient
pregabalin
RxNorm CUI
187832

Indications

Pregabalin capsule is indicated for: Management of neuropathic pain associated with diabetic peripheral neuropathy Management of postherpetic neuralgia Adjunctive therapy for the treatment of partial-onset seizures in patients 1month of age and older Management of fibromyalgia Management of neuropathic pain associated with spinal cord injury

Labeler: REMEDYREPACK INC.Updated: 2026-02-25T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

[see Warnings and Precautions (5.2)]. Pregabalin is contraindicated in patients with known hypersensitivity to pregabalin or any of its components. Angioedema and hypersensitivity reactions have occurred in patients receiving pregabalin therapy

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Use of pregabalin and limaprost in the conservative treatment of lumbar spinal stenosis: a systematic review of the current evidence.
Di Cosmo Leonardo, Centini Francesca Romana, El Choueiri Jad et al. · Eur J Clin Pharmacol · 2026
PMID: 41546687Meta-Analysis
Pregabalin in Pregnancy: Major Congenital Malformations, Other Birth Outcomes, and Neurodevelopmental Outcomes.
Andrade Chittaranjan · J Clin Psychiatry · 2026
PMID: 41499180Meta-Analysis
Efficacy and safety of pregabalin for postoperative pain after total hip and knee arthroplasty: a systematic review and meta-analysis.
Ruiz Ibán Miguel Ángel, Oteo-Álvaro Ángel, Miguéns Vázquez Xoán et al. · J Orthop Surg Res · 2025
PMID: 40069801Meta-AnalysisFull text (PMC)
Efficacy and Safety of Pregabalin and Gabapentin for Pruritus: A Systematic Review and Meta-Analysis.
Xu Wenting, Dong Hanyue, Ran Haolong et al. · J Pain Symptom Manage · 2025
PMID: 39173895Meta-Analysis
Does pregabalin offer potential as a first-line therapy for generalized anxiety disorder? A meta-analysis of efficacy, safety, and cost-effectiveness.
Cardoner Narcis, Gutiérrez-Rojas Luis, Saiz Pilar et al. · Front Pharmacol · 2025
PMID: 39989902Meta-AnalysisFull text (PMC)
Cardiovascular safety of gabapentinoids gabapentin & pregabalin: A systematic review.
Dutta Deep, Mohindra Ritin, Kumar Manoj et al. · Indian J Med Res · 2025
PMID: 40536375Meta-AnalysisFull text (PMC)
The use of pregabalin in early pregnancy and major congenital malformations: A systematic review and meta-analysis.
Atzenhoffer Marina, Peron Audrey, Picot Cyndie et al. · Reprod Toxicol · 2025
PMID: 40473046Meta-Analysis
Comparing Gabapentin and Pregabalin for Perioperative Pain Management in Lumbar Spine Surgery: A Systematic Review and Meta-Analysis.
Ebada Ali, Bever Nicholas, Carron Christopher J et al. · World Neurosurg · 2025
PMID: 40653011Meta-Analysis
Efficacy of gabapentin and pregabalin for treatment of post refractive surgery pain: a systematic review and meta-analysis.
Chen Kai-Yang, Chan Hoi-Chun, Wei Li-Yun et al. · Int Ophthalmol · 2024
PMID: 39448432Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Pregabalin (substance)
SNOMED CT
415160008
UMLS CUI
C0657912
RxNorm CUI
187832
Labeler
REMEDYREPACK INC.

Clinical Data

This intervention maps to 6 entities in the Healos knowledge graph.

6
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.