Substance / Medication

Procarbazine

Overview

Active Ingredient
procarbazine
RxNorm CUI
8702

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Procarbazine, lomustine and vincristine for recurrent high-grade glioma.
Parasramka Saurabh, Talari Goutham, Rosenfeld Myrna et al. · Cochrane Database Syst Rev · 2017
PMID: 28744879Meta-AnalysisFull text (PMC)
Benefit from procarbazine, lomustine, and vincristine in oligodendroglial tumors is associated with mutation of IDH.
Cairncross J Gregory, Wang Meihua, Jenkins Robert B et al. · J Clin Oncol · 2014
PMID: 24516018RCTFull text (PMC)
Treatment outcomes of ABVD in classical Hodgkin lymphoma patients from Thailand without procarbazine access.
Suttantapidok Suprang, Kungwankiattichai Smith, Owattanapanich Weerapat · Sci Rep · 2025
PMID: 40595106ObservationalFull text (PMC)
Adsorption of procarbazine anticancer drug over Cand BNnanocages: A comparative DFT study.
Celaya Christian A, Martínez Del Sobral Sinitsyna Carmen, Hernández-Ayala Luis Felipe et al. · J Mol Graph Model · 2025
PMID: 40435552Observational
Regimen of procarbazine, lomustine, and vincristine versus temozolomide for gliomas.
Wick Wolfgang, Winkler Frank · Cancer · 2018
PMID: 29698549Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Procarbazine (substance)
SNOMED CT
387474003
UMLS CUI
C0033223
RxNorm CUI
8702

Clinical Data

This intervention maps to 7 entities in the Healos knowledge graph.

7
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.