Substance / Medication

Promethazine hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

71 trials linked to this intervention

71
Total Trials
9
Recruiting
23
With Results

Research Evidence

Published studies and systematic reviews

Sort:
The Effectiveness and Safety of Cupping Therapy on CV8 Shenque for Urticaria: A Systematic Review and Meta‑Analysis.
Chae Soo-Yeon, Sung Won-Suk, Kim Eun-Jung et al. · Altern Ther Health Med · 2025
PMID: 39715564Meta-Analysis
Excipient induced allergies in oral medications: unravelling the covert threat - a systematic review.
Seth Shrey, Lukose Lipin, Sud Kamal et al. · Intern Med J · 2025
PMID: 39718818Meta-Analysis
The risk of donor-acquired allergy in solid-organ transplant recipients: A systematic review.
Lee Erika Yue, Sohng Kaylee, Singer Lianne G et al. · Ann Allergy Asthma Immunol · 2025
PMID: 39863119Meta-Analysis
Evaluation of Pharmacological Treatments for Acute Urticaria: A Systematic Review and Meta-Analysis.
Jamjanya Sirinda, Danpanichkul Pojsakorn, Ongsupankul Sorawit et al. · J Allergy Clin Immunol Pract · 2024
PMID: 38280453Meta-Analysis
Efficacy and Safety of Systemic Corticosteroids for Urticaria: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
Chu Xiajing, Wang Jason, Ologundudu Leonardo et al. · J Allergy Clin Immunol Pract · 2024
PMID: 38642709Meta-Analysis
Leukotriene receptor antagonists as add-on therapy to antihistamines for urticaria: Systematic review and meta-analysis of randomized clinical trials.
Rayner Daniel G, Liu Ming, Chu Alexandro W L et al. · J Allergy Clin Immunol · 2024
PMID: 38852861Meta-Analysis
Why fexofenadine is considered as a truly non-sedating antihistamine with no brain penetration: a systematic review.
Ansotegui Ignacio J, Bousquet Jean, Canonica Giorgio Walter et al. · Curr Med Res Opin · 2024
PMID: 39028636Meta-Analysis
The prevelance of food allergy in patients with chronic idiopathic urticaria: a systematic review and meta-analysis.
Alotaibi Hend M, Alghamdi Asail S, Almutairi Rahaf Tayi et al. · Arch Dermatol Res · 2024
PMID: 39680174Meta-Analysis
Pharmacokinetics of promethazine hydrochloride after administration of rectal suppositories and oral syrup to healthy subjects.
Strenkoski-Nix L C, Ermer J, DeCleene S et al. · Am J Health Syst Pharm · 2000
PMID: 10965395Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Promethazine hydrochloride (substance)
SNOMED CT
14905007
UMLS CUI
C0546876

Clinical Data

This intervention maps to 7 entities in the Ltrl knowledge graph.

7
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
71
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.