No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

4 trials linked to this intervention

Total Trials

Recruiting

With Results

Recent Trials

Efficacy of Albendazole to Treat Intestinal Helminths and Its Effect on Gut Microflora

NCT01192802Phase 4Completed200 enrolled

Impact of Alternative Treatment Strategies and Delivery Systems for Soil-transmitted Helminths in Kenya

NCT02397772Phase 4Completed21761 enrolled

Triple Combinations Against Hookworm Infections in Lao

NCT03278431Phase 4Completed420 enrolled

Moxidectin Versus Ivermectin as Mass Drug Administration for the Control of Onchocerciasis and Other Neglected Tropical Diseases

NCT07145736Phase 4Recruiting52000 enrolled

View all 4 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

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A randomized assessors-blind clinical trial to evaluate the safety and the efficacy of albendazole alone and in combination with mebendazole or pyrantel for the treatment ofinfection in school-aged children in Lambaréné and surroundings.

Nguema Moure Paul Alvyn, Nzamba Maloum Moustapha, Manouana Gédéon Prince et al. · Antimicrob Agents Chemother · 2024

PMID: 38563751RCTFull text (PMC)

The efficacy of ivermectin, pyrantel and fenbendazole against Parascaris equorum infection in foals on farms in Australia.

Armstrong S K, Woodgate R G, Gough S et al. · Vet Parasitol · 2014

PMID: 25224788RCT

Plasma pharmacokinetics, faecal excretion and efficacy of pyrantel pamoate paste and granule formulations following per os administration in donkeys naturally infected with intestinal strongylidae.

Gokbulut Cengiz, Aksit Dilek, Smaldone Giorgio et al. · Vet Parasitol · 2014

PMID: 25015542RCT

Efficacy of a combination product containing pyrantel, febantel and praziquantel (Drontal Plus Flavour, Bayer Animal Health) against experimental infection with the hookworm Ancylostoma ceylanicum in dogs.

Taweethavonsawat Piyanan, Chungpivat Sudchit, Satranarakun Pakkawan et al. · Parasitol Res · 2010

PMID: 19911198RCT

Efficacy of Drontal Flavour Plus (50 mg praziquantel, 144 mg pyrantel embonate, 150 mg febantel per tablet) against Giardia sp in naturally infected dogs.

Montoya Ana, Dado Diana, Mateo Marta et al. · Parasitol Res · 2008

PMID: 18661153RCT

Macrocyclic lactone-resistant Parascaris equorum on stud farms in Canada and effectiveness of fenbendazole and pyrantel pamoate.

Slocombe J Owen D, de Gannes Rolph V G, Lake Mary C · Vet Parasitol · 2007

PMID: 16962243RCT

Dose-confirmation studies of the cestocidal activity of pyrantel pamoate paste in horses.

Reinemeyer Craig R, Hutchens Douglas E, Eckblad Wm P et al. · Vet Parasitol · 2006

PMID: 16530970RCT

Target animal safety and tolerance study of pyrantel pamoate paste (19.13% w/w pyrantel base) administered orally to horses.

Marchiondo Alan A, TerHune Terry N, Herrick Robert L · Vet Ther · 2005

PMID: 16550493RCT

Field efficacy and safety evaluation of a novel chewable tablet (Credelio Quattro™) containing lotilaner, moxidectin, praziquantel, and pyrantel against gastrointestinal nematode infections in dogs in the USA.

Charles Samuel, Wiseman Scott, Savadelis Molly D et al. · Parasit Vectors · 2025

PMID: 40713857ObservationalFull text (PMC)

Comparison of the initial and residual speed of Amblyomma americanum kill on dogs treated with a single dose of Bravecto® Chew (25 mg/kg fluralaner) or Simparica TRIO® (1.2 mg/kg sarolaner, 24 µg/kg moxidectin, 5 mg/kg pyrantel).

Reif Kathryn E, Dryden Michael W, Normile Dorothy M et al. · Parasit Vectors · 2025

PMID: 40119355ObservationalFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Pyrantel (substance)
SNOMED CT: 387193008
UMLS CUI: C0034235
RxNorm CUI: 8984

Clinical Data

This intervention maps to 5 entities in the Healos knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.