Substance / Medication

Pyridostigmine

Overview

Active Ingredient
pyridostigmine
RxNorm CUI
9000

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

19 trials linked to this intervention

19
Total Trials
16
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Pyridostigmine in the management of orthostatic hypotension: a systematic review and meta-analysis.
Pavic Nicholas Vlado, Zhang Shane, Maloof Alexander George et al. · Open Heart · 2025
PMID: 40132893Meta-AnalysisFull text (PMC)
Pyridostigmine for the Management of Neurogenic Orthostatic Hypotension: A Systemic Review.
Holder Amanda C, Dylewski Angela, Brown Jamie N · J Geriatr Psychiatry Neurol · 2025
PMID: 39043171Meta-Analysis
Pyridostigmine in chronic intestinal pseudo-obstruction - a systematic review.
Wilkie Bruce D, Noori Jawed, Johnston Michael et al. · ANZ J Surg · 2023
PMID: 37132128Meta-Analysis
Clinical Correlates of Efficacy of Pyridostigmine in the Treatment of Orthostatic Hypotension.
Okamoto Luis E, Walsh Emily, Diedrich Andre et al. · Hypertension · 2025
PMID: 39727053RCTFull text (PMC)
Pyridostigmine to Reduce the duration of postoperative Ileus after Colorectal surgery (PyRICo-RCT): randomized clinical trial.
Traeger Luke, Bedrikovetski Sergei, Fitzsimmons Tracy et al. · Br J Surg · 2024
PMID: 38743864RCT
Enhanced low-threshold motor unit capacity during endurance tasks in patients with spinal muscular atrophy using pyridostigmine.
Habets Laura E, Bartels Bart, Jeneson Jeroen A L et al. · Clin Neurophysiol · 2023
PMID: 37595479RCT
Pyridostigmine reduces mortality of patients with severe SARS-CoV-2 infection: A phase 2/3 randomized controlled trial.
Fragoso-Saavedra Sergio, Núñez Isaac, Audelo-Cruz Belem M et al. · Mol Med · 2022
PMID: 36348276RCTFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Pyridostigmine (substance)
SNOMED CT
373344003
UMLS CUI
C0034261
RxNorm CUI
9000

Clinical Data

This intervention maps to 1 entities in the Healos knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
19
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.