Substance / Medication

Quinine sulfate

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Quinine Sulfate for Muscle Cramps in Amyotrophic Lateral Sclerosis: A Randomized, Double-Blind Crossover Trial.
Vogt Charlotte, Weber Markus, Schneider Ursula et al. · Muscle Nerve · 2025
PMID: 40384575RCT
Use of an active surveillance system by the FDA to observe patterns of quinine sulfate use and adverse hematologic outcomes in CMS Medicare data.
Houstoun Monika, Reichman Marsha E, Graham David J et al. · Pharmacoepidemiol Drug Saf · 2014
PMID: 24872151Observational
Oral quinine sulfate for the treatment of electrical storm and prevention of recurrent shocks in Brugada syndrome after failed cilostazol therapy.
Shenthar Jayaprakash, Chakali Siva Sankara, Acharya Debashish et al. · HeartRhythm Case Rep · 2017
PMID: 29062700Case ReportFull text (PMC)
Quinine sulfate as a therapeutic option in a patient with slow channel congenital myasthenic syndrome.
Peyer Anne-Kathrin, Abicht Angela, Heinimann Karl et al. · Neuromuscul Disord · 2013
PMID: 23688972Case Report
Transient pulmonary infiltrates possibly induced by quinine sulfate.
Krantz Mori J, Dart Richard C, Mehler Philip S · Pharmacotherapy · 2002
PMID: 12066969Case Report
[Acral necroses after therapy with quinine sulfate for calf cramps].
Abreu-Gerke L, Goerz G, Miller A et al. · Hautarzt · 2000
PMID: 10875070Case Report

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Quinine sulfate (substance)
SNOMED CT
47857006
UMLS CUI
C0034422

Clinical Data

This intervention maps to 4 entities in the Healos knowledge graph.

4
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.