Substance / Medication

Secukinumab

Overview

Active Ingredient
secukinumab
RxNorm CUI
1599788
Labeler: Novartis Pharmaceuticals CorporationUpdated: 2025-12-12T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

[see Warnings and Precautions (5.2)] COSENTYX is contraindicated in patients with a previous serious hypersensitivity reaction to secukinumab or to any of the excipients in COSENTYX. Cases of anaphylaxis and angioedema have been reported during treatment with COSENTYX.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

22 trials linked to this intervention

22
Total Trials
4
Recruiting
10
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Real World Evidence of Secukinumab and Bimekizumab in Hidradenitis Suppurativa: A Systematic Review and Meta-Analysis.
Haselgruber S, Muñoz-Barba D, Soto-Moreno A et al. · Actas Dermosifiliogr · 2026
PMID: 41349691Meta-Analysis
Efficacy and Safety of Secukinumab for the Treatment of Psoriasis: A Meta-Analysis of Pivotal Phase III Trials.
Zhou Yu, Zhang Kaihui, Ma Xueting et al. · Dermatology · 2024
PMID: 37926074Meta-Analysis
Comparative efficacy of secukinumab against adalimumab and infliximab in patients with moderate-to-severe plaque psoriasis.
Pan Ran, Wang Xiaolun, Shu Min et al. · Chin Med J (Engl) · 2022
PMID: 34882622Meta-AnalysisFull text (PMC)
Secukinumab Efficacy in Psoriatic Arthritis: Machine Learning and Meta-analysis of Four Phase 3 Trials.
Gottlieb Alice B, Mease Philip J, Kirkham Bruce et al. · J Clin Rheumatol · 2021
PMID: 32015257Meta-AnalysisFull text (PMC)
Efficacy and safety of secukinumab in patients with psoriatic arthritis: A meta-analysis of different dosing regimens.
Zhang Kai-Lin, Hou Si-Yuan, Wu Dan · Clinics (Sao Paulo) · 2021
PMID: 34614111Meta-AnalysisFull text (PMC)
Short-Term Efficacy and Safety of Secukinumab for Ankylosing Spondylitis: A Systematic Review and Meta-Analysis of RCTs.
Zhou Yu, Ma Jinhui, Ge Juncheng et al. · Mediators Inflamm · 2020
PMID: 33192173Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Secukinumab (substance)
SNOMED CT
708822004
UMLS CUI
C3179547
RxNorm CUI
1599788
Labeler
Novartis Pharmaceuticals Corporation

Clinical Data

This intervention maps to 2 entities in the Healos knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
22
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.