Substance / Medication

Sodium acetate

Overview

Active Ingredient
sodium acetate
RxNorm CUI
56443

Indications

INDICATIONS AND USAGE Sodium Acetate Injection, USP is indicated as a source of sodium for addition to large volume intravenous fluids to prevent or correct hyponatremia in patients with restricted or no oral intake. It is also useful as an additive for preparing specific intravenous fluid formulas when the needs of the patient cannot be met by standard electrolyte or nutrient solutions.

Labeler: MILLA PHARMACEUTICALS INC.Updated: 2026-01-07T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

CONTRAINDICATIONS Sodium Acetate Injection, USP is contraindicated in patients with hypernatremia or fluid retention.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

1 trials linked to this intervention

1
Total Trials
1
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
The Role of Dietary Acid Load on Progression of Estimated Glomerular Filtration Rate Among Individuals Diagnosed With Chronic Kidney Disease.
Poyourow Christina Nina, Leonberg Kristin, Ghajar Mina et al. · J Ren Nutr · 2024
PMID: 38490515Meta-Analysis
Effect of Sodium Bicarbonate on Systolic Blood Pressure in CKD: A Systematic Review and Meta-Analysis.
Beynon-Cobb Beverley, Louca Panayiotis, Hoorn Ewout J et al. · Clin J Am Soc Nephrol · 2023
PMID: 36758154Meta-AnalysisFull text (PMC)
Expanding the evidence for managing metformin poisoning to support decision-making.
Roberts Darren M, Ghannoum Marc · Clin Toxicol (Phila) · 2023
PMID: 37129225Meta-Analysis
Systematic review of the relationship between rumen acidosis and laminitis in cattle.
Passos Lorena Teixeira, Bettencourt Arthur Fernandes, Ritt Luciano Antônio et al. · Res Vet Sci · 2023
PMID: 37356405Meta-Analysis
Effects of correcting metabolic acidosis on muscle mass and functionality in chronic kidney disease: a systematic review and meta-analysis.
Visser Wesley J, van de Braak Elma E M, de Mik-van Egmond Anneke M E et al. · J Cachexia Sarcopenia Muscle · 2023
PMID: 37728018Meta-AnalysisFull text (PMC)
[Effect of sodium acetate Ringer injection on perioperative fluid therapy in children with cyanotic congenital heart disease].
Wang Lu, Zhang Ruidong · Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · 2019
PMID: 30914102RCT
The effect of sodium acetate ingestion on the metabolic response to prolonged moderate-intensity exercise in humans.
Smith Gordon I, Jeukendrup Asker E, Ball Derek · Int J Sport Nutr Exerc Metab · 2013
PMID: 23296954RCT
13C-sodium acetate breath test for evaluation of gastric emptying times in dogs with gastric dilatation-volvulus.
Schmitz S, Jansen N, Failing K et al. · Tierarztl Prax Ausg K Kleintiere Heimtiere · 2013
PMID: 23608963Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Sodium acetate (substance)
SNOMED CT
108951007
UMLS CUI
C0142785
RxNorm CUI
56443
Labeler
MILLA PHARMACEUTICALS INC.

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
1
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.