Substance / Medication

Solifenacin succinate

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Instability of bladder

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:

Efficacy of Additional Solifenacin Succinate Therapy for Storage Symptoms in Females with Uncomplicated Lower Urinary Tract Infection: The SOLUTION Randomized Controlled Trial.

Rahardjo Harrina Erlianti, Syahputra Firtantyo Adi, Islianti Putri Iradita et al. · Acta Med Indones · 2018

PMID: 30333269RCT

Efficacy and safety of tamsulosin hydrochloride 0.2 mg and combination of tamsulosin hydrochloride 0.2 mg plus solifenacin succinate 5 mg after transurethral resection of the prostate: a prospective, randomized controlled trial.

Shin Yu Seob, Zhang Li Tao, You Jae Hyung et al. · Clin Interv Aging · 2016

PMID: 27698559RCTFull text (PMC)

The therapeutic effect of solifenacin succinate on the recovery from voiding dysfunction after radical prostatectomy in men with clinically localized prostate cancer: a prospective, randomized, controlled study.

Shim Myungsun, Kim Jongwon, Park Sejun et al. · Urology · 2015

PMID: 25746580RCT

[A combination of solifenacin succinate and naftopidil in the treatment of female overactive bladder].

Huo Li-zhi, Jing Han-guo, Wang Teng-chun et al. · Zhonghua Yi Xue Za Zhi · 2013

PMID: 24521895RCT

Transcutaneous electrical nerve stimulation and solifenacin succinate versus solifenacin succinate alone for treatment of overactive bladder syndrome: A double-blind randomized controlled study.

Zhang Yumeng, Wang Shaoyong, Zu Shulu et al. · PLoS One · 2021

PMID: 34161360ObservationalFull text (PMC)

Efficacy and Safety of Gabapentin in Comparison to Solifenacin Succinate in Adult Overactive Bladder Treatment.

Chua Michael E, See Manuel C, Esmeňa Ednalyn B et al. · Low Urin Tract Symptoms · 2018

PMID: 28150436Observational

A randomized, multicenter, controlled study, comparing efficacy and safety of a new complementary and alternative medicine (CAM) versus Solifenacin Succinate in women with overactive bladder syndrome.

Vecchioli-Scaldazza Carlo, Morosetti Carolina, Maruccia Serena et al. · Arch Ital Urol Androl · 2017

PMID: 29473382Observational

Efficacy and safety of solifenacin succinate tablets versus solifenacin succinate tablets with local estrogen for the treatment of overactive bladder in postmenopausal women--a multicenter, randomized, open-label, controlled comparison study.

Jiang Fang, Zhu Lan, Xu Tao et al. · Menopause · 2016

PMID: 26757270Observational

Comparison of Therapeutic Efficacy and Urodynamic Findings of Solifenacin Succinate versus Mirabegron in Women with Overactive Bladder Syndrome: Results of a Randomized Controlled Study.

Vecchioli Scaldazza Carlo, Morosetti Carolina · Urol Int · 2016

PMID: 27092789Observational

Randomized, controlled pilot trial of solifenacin succinate for overactive bladder in Parkinson's disease.

Zesiewicz Theresa A, Evatt Marian, Vaughan Camille P et al. · Parkinsonism Relat Disord · 2015

PMID: 25814050Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Solifenacin succinate (substance)
SNOMED CT: 426324001
UMLS CUI: C1509436

Clinical Data

This intervention maps to 1 entities in the Healos knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.