Back to Interventions
Substance / Medication

Sorbitol

SNOMED 19839007UMLS C0037688

Overview

Active Ingredient
sorbitol
RxNorm CUI
9945

Indications

Sorbitol-Mannitol Irrigation is indicated for use as a urologic irrigating fluid during transurethral prostatic resection and other transurethral surgical procedures.

Labeler: ICU Medical Inc.Updated: 2025-10-30T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

NOT FOR INJECTION BY USUAL PARENTERAL ROUTES. Do not use in patients with anuria.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Poisoning

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

2 trials linked to this intervention

2
Total Trials
1
Recruiting
0
With Results

Recent Trials

Glucagon's Cardiovascular Effects With and Without Beta-blocker-induced Cardioinhibition

NCT03533179Phase 4Completed10 enrolled

Activated CHARcoal in Poisoned Patient - Pilot Trial

NCT05471479Phase 4Recruiting100 enrolled
View all 2 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:
Efficacy and safety of a New D-sorbitol, Ascorbic Acid, and Picosulfate Bowel Cleansing Solution for colonoscopy: A prospective, multicenter, randomized study.
Shin Seung Yong, Lee Yoo Jin, Jung Yunho et al. · Dig Liver Dis · 2025
PMID: 41188168RCT
Effect of single-administration of D-sorbitol pretreatment on the bitterness and continued willingness to take asenapine: a randomized, single-blind, placebo-controlled, crossover trial.
Wada Shuhei, Iwamoto Kunihiro, Okumura Hiroki et al. · BMC Psychiatry · 2024
PMID: 38291403RCTFull text (PMC)
Sensory evaluation of the bitterness of asenapine using D-sorbitol pretreatment: single-blind, placebo-controlled, crossover trial.
Wada Shuhei, Iwamoto Kunihiro, Okumura Hiroki et al. · BMC Psychiatry · 2023
PMID: 36918838RCTFull text (PMC)
Prune Juice Containing Sorbitol, Pectin, and Polyphenol Ameliorates Subjective Complaints and Hard Feces While Normalizing Stool in Chronic Constipation: A Randomized Placebo-Controlled Trial.
Koyama Taishi, Nagata Naoyoshi, Nishiura Kengo et al. · Am J Gastroenterol · 2022
PMID: 35971232RCTFull text (PMC)
Assessment of the Response Profile to Hyaluronic Acid Plus Sorbitol Injection in Patients with Knee Osteoarthritis: Post-Hoc Analysis of a 6-Month Randomized Controlled Trial.
Bruyère Olivier, Honvo Germain, Vidovic Eduard et al. · Biomolecules · 2021
PMID: 34680131RCTFull text (PMC)
Effect of Sorbitol on the Pharmacokinetic Profile of Lamivudine Oral Solution in Adults: An Open-Label, Randomized Study.
Adkison Kimberly, Wolstenholme Allen, Lou Yu et al. · Clin Pharmacol Ther · 2018
PMID: 29150845RCTFull text (PMC)
Dietary sorbitol and mannitol: food content and distinct absorption patterns between healthy individuals and patients with irritable bowel syndrome.
Yao C K, Tan H-L, van Langenberg D R et al. · J Hum Nutr Diet · 2014
PMID: 23909813RCT
Effect of xylitol and sorbitol on plaque acidogenesis.
Splieth Christian H, Alkilzy Mohammad, Schmitt Jan et al. · Quintessence Int · 2009
PMID: 19417872RCT
Fructose-sorbitol ingestion provokes gastrointestinal symptoms in patients with eating disorders.
Friesen Noel, Hansen Ross D, Abraham Suzanne F et al. · World J Gastroenterol · 2009
PMID: 19908337RCTFull text (PMC)
Effect of nonabsorbed amounts of a fructose-sorbitol mixture on small intestinal transit in healthy volunteers.
Madsen Jan L, Linnet Jan, Rumessen Jüri J · Dig Dis Sci · 2006
PMID: 16416228RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Sorbitol (substance)
SNOMED CT
19839007
UMLS CUI
C0037688
RxNorm CUI
9945
Labeler
ICU Medical Inc.

Clinical Data

This intervention maps to 1 entities in the Healos knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
2
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.