No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

1 trials linked to this intervention

Total Trials

Recruiting

With Results

Recent Trials

Temozolomide With or Without Capecitabine in Treating Patients With Advanced Pancreatic Neuroendocrine Tumors

NCT01824875Phase 2Active Not Recruiting144 enrolled

View all 1 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:

Capecitabine and streptozocin ± cisplatin in advanced gastroenteropancreatic neuroendocrine tumours.

Meyer Tim, Qian Wendi, Caplin Martyn E et al. · Eur J Cancer · 2014

PMID: 24445147RCT

Efficacy and safety of streptozocin-based chemotherapy for gastroenteropancreatic neuroendocrine tumors in Japanese clinical practice.

Murakami Masatoshi, Fujimori Nao, Takamatsu Yu et al. · Jpn J Clin Oncol · 2024

PMID: 38422348Observational

Mitochondrial dysfunction contribute to diabetic neurotoxicity induced by streptozocin in mice: protective effect of Urtica dioica and pioglitazone.

Shokrzadeh Mohammad, Mirshafa Atefeh, Yekta Moghaddam Niusha et al. · Toxicol Mech Methods · 2018

PMID: 29606029Observational

Effect of phosphodiesterase inhibitors on renal functions and oxidant/antioxidant parameters in streptozocin-induced diabetic rats.

Mehanna Osama Mahmoud, El Askary Ahmad, Al-Shehri Saad et al. · Arch Physiol Biochem · 2018

PMID: 29271249Observational

Multi-center clinical evaluation of streptozocin-based chemotherapy for advanced pancreatic neuroendocrine tumors in Japan: focus on weekly regimens and monotherapy.

Shibuya Hitoshi, Hijioka Susumu, Sakamoto Yasunari et al. · Cancer Chemother Pharmacol · 2018

PMID: 30054710Observational

Preoperative Fluorouracil, Doxorubicin, and Streptozocin for the Treatment of Pancreatic Neuroendocrine Liver Metastases.

Cloyd Jordan M, Omichi Kiyohiko, Mizuno Takashi et al. · Ann Surg Oncol · 2018

PMID: 29626307ObservationalFull text (PMC)

Chemoembolization of Neuroendocrine Liver Metastases Using Streptozocin and Tris-acryl Microspheres: Embozar (EMBOsphere + ZAnosaR) Study.

Pelage Jean-Pierre, Fohlen Audrey, Mitry Emmanuel et al. · Cardiovasc Intervent Radiol · 2017

PMID: 28035432Observational

Streptozocin chemotherapy for advanced/metastatic well-differentiated neuroendocrine tumors: an analysis of a multi-center survey in Japan.

Aoki Taku, Kokudo Norihiro, Komoto Izumi et al. · J Gastroenterol · 2015

PMID: 25348496ObservationalFull text (PMC)

Hypoglycemic dipeptide cyclo (His-Pro) significantly altered plasma proteome in streptozocin-induced diabetic rats and genetically-diabetic (ob/ob) mice.

Choi Song Ah, Yun Jong Won, Park Hee Sung et al. · Mol Biol Rep · 2013

PMID: 23086277Observational

Effect of ramipril alone compared to ramipril with eplerenone on diabetic nephropathy in streptozocin-induced diabetic rats.

Mavrakanas Thomas A, Cheva Angeliki, Kallaras Konstantinos et al. · Pharmacology · 2010

PMID: 20689340Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Streptozocin (substance)
SNOMED CT: 16915004
UMLS CUI: C0038432
RxNorm CUI: 10114
Labeler: ESTEVE PHARMACEUTICALS, S.A.

Clinical Data

This intervention maps to 4 entities in the Healos knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.