Substance / Medication

Thimerosal

Overview

Active Ingredient
thimerosal
RxNorm CUI
10472

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Neuropsychological performance 10 years after immunization in infancy with thimerosal-containing vaccines.
Tozzi Alberto Eugenio, Bisiacchi Patrizia, Tarantino Vincenza et al. · Pediatrics · 2009
PMID: 19171612RCT
Mercury levels in premature and low birth weight newborn infants after receipt of thimerosal-containing vaccines.
Pichichero Michael E, Gentile Angela, Giglio Norberto et al. · J Pediatr · 2009
PMID: 19560158RCTFull text (PMC)
Skin reactivity to thimerosal and phenol-preserved Montenegro antigen in Brazil.
Fagundes Aline, Marzochi Mauro C A, Perez Maurício et al. · Acta Trop · 2007
PMID: 17227669RCT
A comparative pharmacokinetic estimate of mercury in U.S. Infants following yearly exposures to inactivated influenza vaccines containing thimerosal.
Mitkus Robert J, King David B, Walderhaug Mark O et al. · Risk Anal · 2014
PMID: 24117921Observational
Toxicity of ethylmercury (and Thimerosal): a comparison with methylmercury.
Dórea José G, Farina Marcelo, Rocha João B T · J Appl Toxicol · 2013
PMID: 23401210Observational
A randomized, controlled trial in children to assess the immunogenicity and safety of a thimerosal-free trivalent seasonal influenza vaccine.
Domachowske Joseph B, Blatter Mark, Chandrasekaran Vijayalakshmi et al. · Pediatr Infect Dis J · 2012
PMID: 22333695Observational
Comparative evaluation of phenol and thimerosal as preservatives for a candidate vaccine against American cutaneous leishmaniasis.
Mayrink Wilson, Tavares Carlos Alberto Pereira, Deus Rosangela Barbosa de et al. · Mem Inst Oswaldo Cruz · 2010
PMID: 20209335Observational
Low molecular weight thiols reduce thimerosal neurotoxicity in vitro: modulation by proteins.
Zieminska E, Toczylowska B, Stafiej A et al. · Toxicology · 2010
PMID: 20696200Observational
Expression of metallothionein mRNAs on mouse cerebellum microglia cells by thimerosal and its metabolites.
Minami Takeshi, Miyata Eriko, Sakamoto Yamato et al. · Toxicology · 2009
PMID: 19386279Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Thimerosal (substance)
SNOMED CT
3379001
UMLS CUI
C0039867
RxNorm CUI
10472

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.