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Substance / Medication

Thyroglobulin

SNOMED 23959001 UMLS C0040123

Overview

Active Ingredient

thyroglobulin

RxNorm CUI

10565

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Autoimmune thyroiditis

Neoplasm of thyroid gland

Thyrotoxicosis with or without goiter

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

LOINC 100796-2

name_match

Clinical Trials

3 trials linked to this intervention

3

Total Trials

0

Recruiting

0

With Results

Recent Trials

Is the Routine Pressure Dressing After Thyroidectomy Necessary?

NCT00400465Phase 4Completed116 enrolled

Minimizing Narcotic Analgesics After Endocrine Surgery

NCT03469310Phase 4Completed126 enrolled

Diagnostic Accuracy Study of Indocyanine Green for Parathyroid Perfusion Assessment

NCT03969108Phase 4Completed10 enrolled

View all 3 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:

Diagnostic performance of 2-[F]FDG PET/CT in recurrent differentiated thyroid cancer and elevated antithyroglobulin antibodies: an updated systematic review and bivariate meta-analysis.

Albano Domenico, Piccardo Arnoldo, Rizzo Alessio et al. · Endocrine · 2025

PMID: 39249633Meta-AnalysisFull text (PMC)

Diagnostic Efficiency of Thyroglobulin in Lymph Node Fine-needle Aspiration Washout: A Systematic Review and Meta-analysis.

Yu Chen-Yeh, Chu Edward Hung-Lun, Lin Che-Hsuan et al. · J Clin Endocrinol Metab · 2025

PMID: 40830071Meta-AnalysisFull text (PMC)

Does it work in childhood and adolescence? The predictive role of postoperative/preablative stimulated thyroglobulin levels in paediatric thyroid cancer. A systematic review of the literature.

Piccardo Arnoldo, Fiz Francesco, Bottoni Gianluca et al. · Rev Endocr Metab Disord · 2024

PMID: 37743443Meta-Analysis

The role of preoperative serum thyroglobulin in the diagnosis and treatment of differentiated thyroid cancer: a systematic review and meta-analysis.

Lu Ying, Zhao Hao, Liu ChunHao et al. · Front Oncol · 2024

PMID: 39777353Meta-AnalysisFull text (PMC)

Efficacy of Empirical 131 I Radioiodine Therapy in Well-Differentiated Thyroid Carcinoma Patients With Thyroglobulin-Elevated Negative Iodine Scintigraphy Syndrome : A Systematic Review and Meta-analysis.

Kim Keunyoung, Hong Chae Moon, Ha Mihyang et al. · Clin Nucl Med · 2024

PMID: 38861375Meta-Analysis

Thyroglobulin Antibodies in Women with Recurrent Pregnancy Loss: A Systematic Review and Meta-Analysis.

Huisman Perrine, Krogh Jesper, Nielsen Claus Henrik et al. · Thyroid · 2023

PMID: 37725583Meta-Analysis

The Diagnostic Value ofF-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Differentiated Thyroid Cancer Patients with Elevated Thyroglobulin/Thyroglobulin Antibody Levels and Negative Iodine Scintigraphy: A Systematic Review and Meta-Analysis.

Bang Ji-In, Park Sohyun, Kim Keunyoung et al. · Thyroid · 2023

PMID: 37597200Meta-Analysis

Association of Thyroid Peroxidase Antibodies and Thyroglobulin Antibodies with Thyroid Function in Pregnancy: An Individual Participant Data Meta-Analysis.

Bliddal Sofie, Derakhshan Arash, Xiao Yi et al. · Thyroid · 2022

PMID: 35596568Meta-Analysis

Serum Thyroglobulin Measurement Following Surgery Without Radioactive Iodine for Differentiated Thyroid Cancer: A Systematic Review.

Chou Roger, Dana Tracy, Brent Gregory A et al. · Thyroid · 2022

PMID: 35412871Meta-AnalysisFull text (PMC)

Is thyroglobulin a reliable biomarker of differentiated thyroid cancer in patients treated by lobectomy? A systematic review and meta-analysis.

Giovanella Luca, Ceriani Luca, Garo Maria Luisa · Clin Chem Lab Med · 2022

PMID: 35475431Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Thyroglobulin (substance)
SNOMED CT: 23959001
UMLS CUI: C0040123
RxNorm CUI: 10565

Clinical Data

This intervention maps to 7 entities in the Healos knowledge graph.

6

Conditions

1

Biomarkers

0

Specialists

0

Symptoms

3

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.