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Substance / Medication

Trimipramine

SNOMED 373550009 UMLS C0041056

Overview

Active Ingredient

trimipramine

RxNorm CUI

10834

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Depressive disorder

Affective psychosis

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Calcidiol+ercalcidiol

LOINC 14635-7

secondary

LOINC 2132-9

secondary

LOINC 3016-3

secondary

Clinical Trials

48 trials linked to this intervention

48

Total Trials

5

Recruiting

17

With Results

Recent Trials

Continuation Electroconvulsive Therapy Vs Medication to Prevent Relapses in Patients With Major Depressive Disorder

NCT00000375Phase 4Completed

Antidepressant Treatment of Melancholia in Late Life

NCT00000378Phase 4Completed110 enrolled

Optimizing Electroconvulsive Therapy for Depression

NCT00045916Phase 4Completed340 enrolled

Ethnic Variations in Antidepressant Response

NCT00047671Phase 4Completed400 enrolled

Research Evaluating the Value of Augmenting Medication With Psychotherapy

NCT00057551Phase 4Completed491 enrolled

View all 48 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

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High performance liquid chromatographic determination of ultra traces of two tricyclic antidepressant drugs imipramine and trimipramine in urine samples after their dispersive liquid-liquid microextraction coupled with response surface optimization.

Shamsipur Mojtaba, Mirmohammadi Mehrosadat · J Pharm Biomed Anal · 2014

PMID: 25178259Observational

Adsorptive stripping voltammetric determination of imipramine, trimipramine and desipramine employing titanium dioxide nanoparticles and an Amberlite XAD-2 modified glassy carbon paste electrode.

Sanghavi Bankim J, Srivastava Ashwini K · Analyst · 2013

PMID: 23324861Observational

Outcome in delusional depression comparing trimipramine monotherapy with a combination of amitriptyline and haloperidol--a double-blind multicenter trial.

Künzel Heike E, Ackl Nibal, Hatzinger Martin et al. · J Psychiatr Res · 2009

PMID: 19038406Observational

The effect of trimipramine on dream recall and dream emotions in depressive outpatients.

Schredl Michael, Berger Mathias, Riemann Dieter · Psychiatry Res · 2009

PMID: 19403177Observational

Trimipramine pharmacokinetics after intravenous and oral administration in carriers of CYP2D6 genotypes predicting poor, extensive and ultrahigh activity.

Kirchheiner Julia, Sasse Johanna, Meineke Ingolf et al. · Pharmacogenetics · 2003

PMID: 14646691Observational

A comparative solid-phase extraction study for the simultaneous determination of fluoxetine, amitriptyline, nortriptyline, trimipramine, maprotiline, clomipramine, and trazodone in whole blood by capillary gas-liquid chromatography with nitrogen-phosphorus detection.

Martínez M A, Sánchez de la Torre C, Almarza E · J Anal Toxicol · 2003

PMID: 14516488Observational

Trimipramine for refractory panic attacks.

Cerra Domingo · Am J Psychiatry · 2006

PMID: 16513887Case Report

Galactorrhea during treatment with trimipramine. A case report.

Wolfsperger M, Greil W · Pharmacopsychiatry · 2005

PMID: 16342006Case Report

[Hypotensive cardio-circulatory failure and metabolic acidosis after suicidal intoxication with trimipramine and quetiapine. Case report and background].

Gabel A, Hinkelbein J · Anaesthesist · 2004

PMID: 14749877Case Report

Seizure during combination of trimipramine and bupropion.

Enns M W · J Clin Psychiatry · 2001

PMID: 11465529Case Report

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Internal Medicine Physician

Internal Medicine

NUCC 207R00000X

Psychiatry Physician

Psychiatry & Neurology — Psychiatry

NUCC 2084P0800X

Find a Provider

Health Goals

Goals connected through associated conditions

Support Mental Wellness

Quick Facts

Type: Substance / Medication
Fully Specified Name: Trimipramine (substance)
SNOMED CT: 373550009
UMLS CUI: C0041056
RxNorm CUI: 10834

Clinical Data

This intervention maps to 8 entities in the Healos knowledge graph.

2

Conditions

3

Biomarkers

2

Specialists

0

Symptoms

48

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.