Substance / Medication

Unoprostone isopropyl

Overview

Active Ingredient
isopropyl unoprostone
RxNorm CUI
135313

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Impact of positive airway pressure therapy on intraocular pressure in obstructive sleep apnea: A systematic review.
Singh Mamta, Deokar Kunal, Dutta Siddhartha et al. · Eur J Ophthalmol · 2025
PMID: 38689462Meta-Analysis
Therapeutic efficacy of topical unoprostone isopropyl in retinitis pigmentosa.
Akiyama Masato, Ikeda Yasuhiro, Yoshida Noriko et al. · Acta Ophthalmol · 2014
PMID: 24868583RCT
Low incidence of iris pigmentation and eyelash changes in 2 randomized clinical trials with unoprostone isopropyl 0.15%.
McCarey Bernard E, Kapik Barry M, Kane Frances E et al. · Ophthalmology · 2004
PMID: 15288975Trial
Partial antagonism of endothelin 1-induced vasoconstriction in the human choroid by topical unoprostone isopropyl.
Polska Elzbieta, Doelemeyer Arno, Luksch Alexandra et al. · Arch Ophthalmol · 2002
PMID: 11879139Trial
Additive efficacy of unoprostone isopropyl 0.12% (rescula) to latanoprost 0.005%.
Stewart W C, Sharpe E D, Stewart J A et al. · Am J Ophthalmol · 2001
PMID: 11239866Trial
An evaluation of the effect of unoprostone isopropyl 0.15% on ocular hemodynamics in normal-tension glaucoma patients.
Beano F, Orgül S, Stümpfig D et al. · Graefes Arch Clin Exp Ophthalmol · 2001
PMID: 11372549Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Unoprostone isopropyl (substance)
SNOMED CT
410844009
UMLS CUI
C0527038
RxNorm CUI
135313

Clinical Data

This intervention maps to 3 entities in the Ltrl knowledge graph.

3
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.