Substance / Medication

Valacyclovir

Overview

Active Ingredient
valacyclovir
RxNorm CUI
73645

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

38 trials linked to this intervention

38
Total Trials
3
Recruiting
12
With Results

Research Evidence

Published studies and systematic reviews

Sort:
The effect of valacyclovir on secondary prevention of congenital cytomegalovirus infection.
Chatzakis Christos, Bourgon Nicolas, Fourgeaud Jacques et al. · Best Pract Res Clin Obstet Gynaecol · 2025
PMID: 41175678Meta-Analysis
Effectiveness and safety of prenatal valacyclovir for congenital cytomegalovirus infection: systematic review and meta-analysis.
D'Antonio F, Marinceu D, Prasad S et al. · Ultrasound Obstet Gynecol · 2023
PMID: 36484439Meta-Analysis
Describing the Impact of Maternal Hyperimmune Globulin and Valacyclovir on the Outcomes of Cytomegalovirus Infection in Pregnancy: A Systematic Review.
Fitzpatrick Alyssa, Cooper Celia, Vasilunas Nan et al. · Clin Infect Dis · 2022
PMID: 35438780Meta-Analysis
Neurotoxicity associated with acyclovir and valacyclovir: A systematic review of cases.
Brandariz-Nuñez David, Correas-Sanahuja Marcelo, Maya-Gallego Sara et al. · J Clin Pharm Ther · 2021
PMID: 34146428Meta-Analysis
Valacyclovir versus acyclovir for the treatment of herpes zoster ophthalmicus in immunocompetent patients.
Schuster Alexander K, Harder Björn C, Schlichtenbrede Frank C et al. · Cochrane Database Syst Rev · 2016
PMID: 27841441Meta-AnalysisFull text (PMC)
Asymptomatic CMV infection at birth following maternal primary infection despite valacyclovir treatment and a subsequent negative amniocentesis. Case report.
Toti Maria Stefania, Zammarchi Lorenzo, Pasquini Lucia et al. · Eur J Obstet Gynecol Reprod Biol · 2023
PMID: 37871349RCT
Valacyclovir in Pain Management of Acute Apical Abscesses: A Randomized Placebo-Controlled Double-Blind Pilot Study.
Sabeti Mohammad, Zhong John, Hildebrandt Kevin et al. · J Endod · 2021
PMID: 34363831RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Valaciclovir (substance)
SNOMED CT
96098007
UMLS CUI
C0249458
RxNorm CUI
73645

Clinical Data

This intervention maps to 5 entities in the Healos knowledge graph.

5
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
38
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.