Substance / Medication

Valproate sodium

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

91 trials linked to this intervention

91
Total Trials
16
Recruiting
33
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Retrospective Chart Review of Intravenous Valproate Sodium as a Preventive Treatment for Patients With Chronic Migraine.
Riggins Nina, Ehrlich Annika, Sawhney Henna et al. · Headache · 2020
PMID: 31985052Observational
The critical interaction between valproate sodium and warfarin: case report and review.
Zhou Chenguang, Sui Yi, Zhao Weijin et al. · BMC Pharmacol Toxicol · 2018
PMID: 30285858Case ReportFull text (PMC)
Unusual drug reaction between valproate sodium and meropenem.
Yoon Hyonok, Kim Diana H · Int J Clin Pharm · 2013
PMID: 23483443Case Report
[Aggravation of epilepsy by valproate sodium in a child with cryptogenic localization-related epilepsy].
Watanabe Yoshiaki, Watanabe Kiyoko, Ohtsuka Yoko · No To Hattatsu · 2011
PMID: 21400933Case Report
[Three cases of Fanconi syndrome associated with valproate sodium treatment].
Inoue Takeshi, Tanaka Yuriko, Otani Ryoko et al. · No To Hattatsu · 2011
PMID: 21638910Case Report
Probable valproate sodium-associated hypotension.
Ota Ken S · Am J Geriatr Pharmacother · 2010
PMID: 20624617Case Report
[Valproate sodium is effective as prophylactic therapy for cyclic vomiting syndrome in a case].
Amakata K, Nakamoto N, Hikita T et al. · No To Hattatsu · 2008
PMID: 18341057Case Report
[The effect of prophylactic therapy with valproate sodium and phenobarbital in two patients with cyclic vomiting syndrome].
Hikita Toshiyuki, Kodama Hiroko, Nakamoto Natsue et al. · No To Hattatsu · 2008
PMID: 18807888Case Report
[Clinical observation of valproate sodium-induced nocturnal enuresis].
Yokoyama A, Saito Y, Maegaki Y et al. · No To Hattatsu · 2007
PMID: 17515140Case Report
[Valproate sodium and zonisamide associated interstitial pneumonitis in an infant].
Nikaido Koki, Kato Takahiro, Takayama Rumiko et al. · No To Hattatsu · 2007
PMID: 17228818Case Report

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Sodium valproate (substance)
SNOMED CT
387481005
UMLS CUI
C0037567

Clinical Data

This intervention maps to 9 entities in the Healos knowledge graph.

4
Conditions
3
Biomarkers
1
Specialists
0
Symptoms
91
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.