Substance / Medication

Vincristine

Overview

Active Ingredient
vincristine
RxNorm CUI
11202

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

59 trials linked to this intervention

59
Total Trials
39
Recruiting
5
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Vincristine-induced ptosis in pediatric patients: a systematic review and practice recommendations.
Ahmed H Shafeeq, Thrishulamurthy Chinmayee J · Eur J Pediatr · 2025
PMID: 39994116Meta-Analysis
The impact of vincristine on testicular development and function in childhood cancer.
Clark Ioanna, Brougham Mark F H, Spears Norah et al. · Hum Reprod Update · 2023
PMID: 36495566Meta-AnalysisFull text (PMC)
Impact of vincristine-steroid pulses during maintenance for B-cell pediatric ALL: a systematic review and meta-analysis.
Guolla Louise, Breitbart Sara, Foroutan Farid et al. · Blood · 2023
PMID: 36821772Meta-Analysis
Contribution of common and rare genetic variants in CEP72 on vincristine-induced peripheral neuropathy in brain tumour patients.
Klumpers Marije J, Brand Annouk C A M, Hakobjan Marina et al. · Br J Clin Pharmacol · 2022
PMID: 35150001Meta-AnalysisFull text (PMC)
Pharmacogenomics of Vincristine-Induced Peripheral Neuropathy Implicates Pharmacokinetic and Inherited Neuropathy Genes.
Wright Galen E B, Amstutz Ursula, Drögemöller Britt I et al. · Clin Pharmacol Ther · 2019
PMID: 29999516Meta-AnalysisFull text (PMC)
Aspects of vincristine-induced neuropathy in hematologic malignancies: a systematic review.
Madsen Marie Lindhard, Due Hanne, Ejskjær Niels et al. · Cancer Chemother Pharmacol · 2019
PMID: 31214762Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Vincristine (substance)
SNOMED CT
387126006
UMLS CUI
C0042679
RxNorm CUI
11202

Clinical Data

This intervention maps to 7 entities in the Healos knowledge graph.

7
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
59
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.