Substance / Medication

Zinc acetate

SNOMED 395952003 UMLS C0149368

Overview

Active Ingredient

zinc acetate

RxNorm CUI

58295

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Skin ulcer

Common cold

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

2 trials linked to this intervention

Total Trials

Recruiting

With Results

Recent Trials

Zinc Supplementation Impact in Acute COVID-19 Clinical Outcomes

NCT05778383Phase 4Completed75 enrolled

Study of Zinc for Wilson Disease

NCT00004338Phase 4Completed300 enrolled

View all 2 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:

Zinc acetate lozenges for treating the common cold: an individual patient data meta-analysis.

Hemilä Harri, Petrus Edward J, Fitzgerald James T et al. · Br J Clin Pharmacol · 2016

PMID: 27378206Meta-AnalysisFull text (PMC)

The effectiveness of high dose zinc acetate lozenges on various common cold symptoms: a meta-analysis.

Hemilä Harri, Chalker Elizabeth · BMC Fam Pract · 2015

PMID: 25888289Meta-AnalysisFull text (PMC)

Comparative effects of three mucoadhesive gels containing lidocaine, zinc acetate, and tannic acid on the gag reflex of dental patients: a randomized double-blind clinical trial.

Nikkerdar Nafiseh, Seyedi Hosna, Mirzaeei Shahla et al. · BMC Oral Health · 2024

PMID: 39604959RCTFull text (PMC)

Zinc acetate lozenges for the treatment of the common cold: a randomised controlled trial.

Hemilä Harri, Haukka Jari, Alho Marianne et al. · BMJ Open · 2020

PMID: 31980506RCTFull text (PMC)

The long-term effect of a zinc acetate and chlorhexidine diacetate containing mouth rinse on intra-oral halitosis-A randomized clinical trial.

Erovic Ademovski Seida, Mårtensson Carina, Persson Gösta Rutger et al. · J Clin Periodontol · 2017

PMID: 28727160RCT

Chemical sterilisation of Bos indicus bull calves following intratesticular injection of zinc acetate: effects on semen quality and testicular changes.

Cavalieri J, Wang M, Johnson L · Anim Reprod Sci · 2015

PMID: 25752498RCT

The effect of zinc acetate and magnolia bark extract added to chewing gum on volatile sulfur-containing compounds in the oral cavity.

Porciani Pier Francesco, Grandini Simone · J Clin Dent · 2012

PMID: 23210417RCT

Duration and severity of symptoms and levels of plasma interleukin-1 receptor antagonist, soluble tumor necrosis factor receptor, and adhesion molecules in patients with common cold treated with zinc acetate.

Prasad Ananda S, Beck Frances W J, Bao Bin et al. · J Infect Dis · 2008

PMID: 18279051RCT

Randomized, multicenter, active-controlled open-label study of NPC-25, zinc histidine hydrate, (non-inferiority to NOBELZIN™, zinc acetate dihydrate) for patients with hypozincemia.

Asaoka Daisuke, Ishihara Tomomi, Ezoe Sachiko et al. · J Trace Elem Med Biol · 2025

PMID: 39705879Observational

Effects of Zinc Acetate on Serum Zinc Concentrations in Chronic Liver Diseases: a Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial and a Dose Adjustment Trial.

Katayama Kazuhiro, Hosui Atsushi, Sakai Yoshiyuki et al. · Biol Trace Elem Res · 2020

PMID: 31392541ObservationalFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Zinc acetate (substance)
SNOMED CT: 395952003
UMLS CUI: C0149368
RxNorm CUI: 58295

Clinical Data

This intervention maps to 2 entities in the Healos knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.