Substance / Medication

Zinc oxide

Overview

Active Ingredient
zinc oxide
RxNorm CUI
11423
Labeler: REMEDYREPACK INC.Updated: 2025-09-30T00:00:00.000ZFull label on DailyMed

Boxed Warning

FDA Black Box Warning

Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under six. Keep this product out of the reach of children. In case of accidental overdose, call a Physician or Poison Control Center immediately.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

19 trials linked to this intervention

19
Total Trials
3
Recruiting
5
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Intraperitoneal hepatorenal toxicity of zinc oxide and nickel oxide nanoparticles in rats: a systematic review.
Kahil Nour, Abouzeinab Noura S, Hussein Mohamed A A et al. · Nanotoxicology · 2024
PMID: 39319754Meta-Analysis
Ecotoxicological effects of zinc oxide nanoparticles (ZnO-NPs) on aquatic organisms: Current research and emerging trends.
Bordin Eduarda Roberta, Ramsdorf Wanessa Algarte, Lotti Domingos Luana Maria et al. · J Environ Manage · 2024
PMID: 37890295Meta-Analysis
Alternative root canal filling materials to zinc oxide eugenol in primary teeth: a systematic review of the literature.
Rhaiem M, Elelmi Y, Baaziz A et al. · Eur Arch Paediatr Dent · 2023
PMID: 37803184Meta-Analysis
Meta-analysis of in-vitro cytotoxicity evaluation studies of zinc oxide nanoparticles: Paving way for safer innovations.
Kad Anaida, Pundir Archit, Arya Shailendra Kumar et al. · Toxicol In Vitro · 2022
PMID: 35724836Meta-Analysis
Potential risks and benefits of zinc oxide nanoparticles: a systematic review.
Keerthana S, Kumar A · Crit Rev Toxicol · 2020
PMID: 32186437Meta-Analysis
Evaluation of the effect of time on the distribution of zinc oxide nanoparticles in tissues of rats and mice: a systematic review.
Chen Aijie, Feng Xiaoli, Sun Ting et al. · IET Nanobiotechnol · 2016
PMID: 27256887Meta-AnalysisFull text (PMC)
A 4-year follow-up of root canal obturation using a calcium silicate-based sealer and a zinc oxide-eugenol sealer: A randomized clinical trial.
Bardini Giulia, Bellido Montse Mercade, Rossi-Fedele Giampiero et al. · Int Endod J · 2025
PMID: 39655615RCTFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Zinc oxide (substance)
SNOMED CT
42841002
UMLS CUI
C0043491
RxNorm CUI
11423
Labeler
REMEDYREPACK INC.

Clinical Data

This intervention maps to 9 entities in the Healos knowledge graph.

4
Conditions
2
Biomarkers
2
Specialists
0
Symptoms
19
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.