Substance / Medication

Zoledronic acid

Overview

Active Ingredient
zoledronic acid
RxNorm CUI
77655

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

14 trials linked to this intervention

14
Total Trials
3
Recruiting
3
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Cardiovascular safety of zoledronic acid in the treatment of primary osteoporosis: A meta-analysis and systematic review.
Liu ShuangHua, Tan YiMei, Huang WeiDong et al. · Semin Arthritis Rheum · 2024
PMID: 37984227Meta-Analysis
Effects of zoledronic acid on osteosarcoma progression and metastasis: systematic review and meta-analysis.
Christou Andrea, Ferreira Nuno, Sophocleous Antonia · Clin Exp Med · 2023
PMID: 36527511Meta-Analysis
The effects of neoadjuvant zoledronic acid in breast cancer patients: A meta-analysis of randomized controlled trials.
Liu Mei, Qian Shengqiang, Wu Jing et al. · Asian J Surg · 2023
PMID: 36732184Meta-Analysis
Efficacy and Safety of Annual Infusion of Zoledronic Acid and Weekly Oral Alendronate in the Treatment of Primary Osteoporosis: A Meta-Analysis.
Wang Qiuling, Yu Qingzhen, Zeng Ping et al. · J Clin Pharmacol · 2023
PMID: 36433675Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Zoledronic acid (substance)
SNOMED CT
395926009
UMLS CUI
C0257685
RxNorm CUI
77655

Clinical Data

This intervention maps to 3 entities in the Healos knowledge graph.

3
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
14
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.