Hemophilia A

disorder

SNOMED 28293008CUI C0019069

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Treatments & Interventions

Coagulation factor VII

substance

Anti-inhibitor coagulant complex

substance

Antihaemophilic factor

substance

Recombinant coagulation factor IX

substance

Porcine antihaemophilic factor agent

substance

Porcine factor VIII

substance

Nonacog alfa

substance

Moroctocog alfa

substance

Simoctocog alfa

substance

Susoctocog alfa

substance

Turoctocog alfa

substance

Emicizumab

substance

Efanesoctocog alfa

substance

Lonoctocog alfa

substance

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Arthritic pain

Very frequent (80-99%)HP:0002829

Bruising susceptibility

Very frequent (80-99%)HP:0000978

Easy bleeding

Very frequent (80-99%)HP:0011889

Factor VIII deficiency

Very frequent (80-99%)HP:0003125

Joint swelling

Very frequent (80-99%)HP:0001386

Excessive bleeding after minor trauma

Frequent (30-79%)HP:0001934

Oral cavity bleeding

Frequent (30-79%)HP:0030140

Spontaneous hematomas

Frequent (30-79%)HP:0007420

Thromboembolic events

Frequent (30-79%)HP:0001907

Abnormality of the elbow

Occasional (5-29%)HP:0009811

Black faeces

Occasional (5-29%)HP:0002249

Bleeding gums

Occasional (5-29%)HP:0000225

Gastrointestinal haemorrhage

Occasional (5-29%)HP:0002239

Hematemesis

Occasional (5-29%)HP:0002248

Intramuscular haematoma

Occasional (5-29%)HP:0012233

Intraventricular hemorrhage

Occasional (5-29%)HP:0030746

Joint hemorrhage

Occasional (5-29%)HP:0005261

Nasal hemorrhage

Occasional (5-29%)HP:0000421

Intracranial haemorrhage

Very rare (1-4%)HP:0002170

Petechiae

Very rare (1-4%)HP:0000967

Red or purple spots on the skin

Very rare (1-4%)HP:0000979

Ruptured spleen

Very rare (1-4%)HP:0012223

Intramuscular hemorrhage

HP:0040242

Osteoarthritis

HP:0002758

Prolonged activated partial thromboplastin time

HP:0003645

Related Conditions

Haemophilia A with inhibitor(child)

Severe hemophilia A(child)

Mild hemophilia A(child)

Moderate hemophilia A(child)

Hereditary factor VIII deficiency disease without inhibitor(child)

X-linked hereditary disease(parent)

Hemophilia(parent)

Hereditary coagulation factor deficiency(parent)

Factor VIII deficiency(parent)

Quick Facts

SNOMED CT: 28293008
UMLS CUI: C0019069
Fully Specified Name: Hereditary factor VIII deficiency disease (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 25
Known Treatments: 14

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.