Myelofibrosis

disorder

SNOMED 52967002CUI C0001815

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Treatments & Interventions

Busulphan

substance

Ruxolitinib

substance

Ruxolitinib phosphate

substance

Fedratinib

substance

Fedratinib hydrochloride

substance

Momelotinib

substance

Momelotinib dihydrochloride monohydrate

substance

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Myelofibrosis

Always present (100%)HP:0011974

Bone marrow disease

Very frequent (80-99%)HP:0005561

Abnormal megakaryocyte morphology

Frequent (30-79%)HP:0012143

Constitutional symptom

Frequent (30-79%)HP:0025142

Enlarged liver

Frequent (30-79%)HP:0002240

Hematologic disease

Frequent (30-79%)HP:0001871

Hepatosplenomegaly

Frequent (30-79%)HP:0001433

Large spleen

Frequent (30-79%)HP:0001744

Low number of red blood cells or haemoglobin

Frequent (30-79%)HP:0001903

Paleness

Frequent (30-79%)HP:0000980

Thrombocytopenia

Frequent (30-79%)HP:0001873

Tiredness

Frequent (30-79%)HP:0012378

Abnormal thrombosis

Occasional (5-29%)HP:0001977

Anorexia

Occasional (5-29%)HP:0002039

Bleeding tendency

Occasional (5-29%)HP:0001892

Blood clot in artery

Occasional (5-29%)HP:0004420

Blood clot in vein

Occasional (5-29%)HP:0004936

Bone marrow hypercellularity

Occasional (5-29%)HP:0031020

Ecchymosis

Occasional (5-29%)HP:0031364

Extramedullary erythropoiesis

Occasional (5-29%)HP:0001978

Increased total leukocyte count

Occasional (5-29%)HP:0001974

Kidney pain

Occasional (5-29%)HP:0030157

Lymph node hyperplasia

Occasional (5-29%)HP:0002716

Mild fever

Occasional (5-29%)HP:0011134

Pancytopenia

Occasional (5-29%)HP:0001876

Petechiae

Occasional (5-29%)HP:0000967

Poikilocytosis

Occasional (5-29%)HP:0004447

Portal hypertension

Occasional (5-29%)HP:0001409

Pyrexia

Occasional (5-29%)HP:0001945

Red or purple spots on the skin

Occasional (5-29%)HP:0000979

Related Conditions

Acute myelofibrosis(child)

Myelosclerosis with myeloid metaplasia(child)

Ischemic myelofibrosis(child)

Congenital neutropenia, bone marrow fibrosis, nephromegaly syndrome(child)

Drug induced myelofibrosis(child)

Myelofibrosis due to another disorder(child)

Bone marrow disorder(parent)

Quick Facts

SNOMED CT: 52967002
UMLS CUI: C0001815
Fully Specified Name: Myelofibrosis (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 30
Known Treatments: 7

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.