Myelosclerosis with myeloid metaplasia

disorder

SNOMED 307651005CUI C0001815

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Treatments & Interventions

Busulphan

substance

Ruxolitinib

substance

Ruxolitinib phosphate

substance

Fedratinib

substance

Fedratinib hydrochloride

substance

Momelotinib

substance

Momelotinib dihydrochloride monohydrate

substance

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Bone marrow disease

Very frequent (80-99%)HP:0005561

Abnormal megakaryocyte morphology

Frequent (30-79%)HP:0012143

Constitutional symptom

Frequent (30-79%)HP:0025142

Enlarged liver

Frequent (30-79%)HP:0002240

Hematologic disease

Frequent (30-79%)HP:0001871

Hepatosplenomegaly

Frequent (30-79%)HP:0001433

Large spleen

Frequent (30-79%)HP:0001744

Low number of red blood cells or haemoglobin

Frequent (30-79%)HP:0001903

Paleness

Frequent (30-79%)HP:0000980

Thrombocytopenia

Frequent (30-79%)HP:0001873

Tiredness

Frequent (30-79%)HP:0012378

Abnormal thrombosis

Occasional (5-29%)HP:0001977

Bleeding tendency

Occasional (5-29%)HP:0001892

Blood clot in artery

Occasional (5-29%)HP:0004420

Blood clot in vein

Occasional (5-29%)HP:0004936

Bone marrow hypercellularity

Occasional (5-29%)HP:0031020

Ecchymosis

Occasional (5-29%)HP:0031364

Extramedullary hematopoiesis

Occasional (5-29%)HP:0001978

Flank pain

Occasional (5-29%)HP:0030157

Increased total leukocyte count

Occasional (5-29%)HP:0001974

Mild fever

Occasional (5-29%)HP:0011134

Pancytopenia

Occasional (5-29%)HP:0001876

Petechiae

Occasional (5-29%)HP:0000967

Poikilocytosis

Occasional (5-29%)HP:0004447

Portal hypertension

Occasional (5-29%)HP:0001409

Pyrexia

Occasional (5-29%)HP:0001945

Red or purple spots on the skin

Occasional (5-29%)HP:0000979

Refusing to eat

Occasional (5-29%)HP:0002039

Swollen lymph nodes

Occasional (5-29%)HP:0002716

Thrombocythaemia

Occasional (5-29%)HP:0001894

Related Conditions

Myelofibrosis(parent)

Chronic myeloproliferative disorder (clinical)(parent)

Quick Facts

SNOMED CT: 307651005
UMLS CUI: C0001815
Fully Specified Name: Primary myelofibrosis (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 30
Known Treatments: 7

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.