Substance / Medication

Clomethiazole

Overview

Active Ingredient
chlormethiazole
RxNorm CUI
2372

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Research Evidence

Published studies and systematic reviews

Sort:
[Which alternative to benzodiazepines, Z-pills and other hypnotics for aged people ? Melatonin, valerian, or clomethiazole].
Dumur Jean, Csajka Chantal, Pavec Ombeline et al. · Rev Med Suisse · 2018
PMID: 30422422Meta-Analysis
GABA agonist: clomethiazole.
Vaishnav Anand, Lutsep Helmi L · Curr Med Res Opin · 2002
PMID: 12365830Meta-Analysis
Treatment with clomethiazole is associated with lower rates of premature discharge during alcohol withdrawal.
Hillemacher T, Weinland C, Heberlein A et al. · Pharmacopsychiatry · 2008
PMID: 18651341RCT
The effects of clomethiazole on polysomnographically recorded sleep in healthy subjects.
Gann Horst, Hartig Kerstin, Feige Bernd et al. · Eur Arch Psychiatry Clin Neurosci · 2005
PMID: 15864407Trial
Pharmacokinetics and sedative effects in healthy subjects and subjects with impaired liver function after continuous infusion of clomethiazole.
Centerholt Carina, Ekblom Marianne, Odergren Tomas et al. · Eur J Clin Pharmacol · 2003
PMID: 12734608Trial
Population pharmacokinetics of clomethiazole and its effect on the natural course of sedation in acute stroke patients.
Zingmark Per-Henrik, Ekblom Marianne, Odergren Tomas et al. · Br J Clin Pharmacol · 2003
PMID: 12895190TrialFull text (PMC)
Clinical trial of the neuroprotectant clomethiazole in coronary artery bypass graft surgery: a randomized controlled trial.
Kong Robert S, Butterworth John, Aveling Wynne et al. · Anesthesiology · 2002
PMID: 12218524Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Clomethiazole (substance)
SNOMED CT
395978007
UMLS CUI
C0008221
RxNorm CUI
2372

Clinical Data

This intervention maps to 9 entities in the Ltrl knowledge graph.

3
Conditions
2
Biomarkers
3
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.