Cortisol

Urine cortisol measurement detects the presence of cortisol, a stress hormone produced by the adrenal glands. This qualitative screening test is used to identify abnormal cortisol production, particularly in suspected Cushing's syndrome (excess cortisol) or adrenal insufficiency (low cortisol). Cortisol regulates blood pressure, glucose, and immune function, so abnormal levels can cause significant health effects. 24-hour urine cortisol is often ordered to confirm results from other cortisol tests.