Substance / Medication

Diphenhydramine hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Research Evidence

Published studies and systematic reviews

Sort:
Antihistaminic and cardiorespiratory effects of diphenhydramine hydrochloride in anesthetized dogs undergoing excision of mast cell tumors.
Sanchez Andrea, Valverde Alexander, Sinclair Melissa et al. · J Am Vet Med Assoc · 2017
PMID: 28967819RCT
Quantitative analysis of diphenhydramine hydrochloride in pharmaceutical wafers using near infrared and Raman spectroscopy.
Haag Maren, Brüning Michael, Molt Karl · Anal Bioanal Chem · 2009
PMID: 19802605Observational
Quantitative analysis of liquid formulations using FT-Raman spectroscopy and HPLC The case of diphenhydramine hydrochloride in Benadryl.
Orkoula M G, Kontoyannis C G, Markopoulou C K et al. · J Pharm Biomed Anal · 2006
PMID: 16621405Observational
Bioequivalence Study of Ibuprofen and Diphenhydramine Hydrochloride mini liquid-filled capsules: A Size Reduction Alternative.
Wyatt David J, Araga Mako, McCloskey Natali et al. · Curr Ther Res Clin Exp · 2025
PMID: 40123879OtherFull text (PMC)
Efficient synthesis of novel thiadiazolo[2,3-b]quinazolin-6-ones catalyzed by diphenhydramine hydrochloride-CoCl⋅6HO deep eutectic solvent.
Korbekandi Mehri Moeini, Mohammadpoor-Baltork Iraj, Moghadam Majid et al. · Sci Rep · 2024
PMID: 38228770OtherFull text (PMC)
Diphenhydramine Hydrochloride-CuCl as a New Catalyst for the Synthesis of Tetrahydrocinnolin-5(1)-ones.
Korbekandi Mehri Moeini, Mohammadpoor-Baltork Iraj, Moghadam Majid et al. · ACS Omega · 2023
PMID: 37179652OtherFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Diphenhydramine hydrochloride (substance)
SNOMED CT
19510001
UMLS CUI
C0004963

Clinical Data

This intervention maps to 9 entities in the Healos knowledge graph.

4
Conditions
1
Biomarkers
2
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.

Diphenhydramine hydrochloride — Conditions, Biomarkers & Specialists | Healos | Healos