Substance / Medication

Digitoxin

Overview

Active Ingredient
digitoxin
RxNorm CUI
3403

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

16 trials linked to this intervention

16
Total Trials
5
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Simple and safe digitoxin dosing in heart failure based on data from the DIGIT-HF trial.
Bavendiek Udo, Großhennig Anika, Schwab Johannes et al. · Clin Res Cardiol · 2023
PMID: 37087503RCTFull text (PMC)
Digitoxin prolongs survival of female rats with heart failure due to large myocardial infarction.
Helber Izo, Dos Santos Alexandra A, Antonio Ednei L et al. · J Card Fail · 2009
PMID: 19879467Observational
A novel LC-IDMS/MS method for the determination of the cardiac glycosides digoxin and digitoxin using caesium adducts.
Kaiser Patricia, Akerboom Theodorus, Wood William Graham et al. · Clin Lab · 2006
PMID: 16506362Observational
Inhibitory effects of digoxin and digitoxin on corticosterone production in rat zona fasciculata-reticularis cells.
Wang Shyi-Wu, Pu Hsaio-Fung, Kan Shu-Fen et al. · Br J Pharmacol · 2004
PMID: 15249423ObservationalFull text (PMC)
Comparing the toxicity of digoxin and digitoxin in a geriatric population: should an old drug be rediscovered?
Roever C, Ferrante J, Gonzalez E C et al. · South Med J · 2000
PMID: 10701788Observational
Of mixed vegetables and cardiac arrhythmias -confused with: A case series of accidental digitoxin intoxications.
Iraci Federica, Herdeg Christian, Holzwarth Martin et al. · J Cardiol Cases · 2023
PMID: 37521578Case ReportFull text (PMC)
Successful Treatment of Severe Digitoxin Intoxication with CytoSorb® Hemoadsorption.
Breuer Thomas Georg Karl, Quast Daniel Robert, Wiciok Stephan et al. · Blood Purif · 2021
PMID: 32937619Case Report

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Digitoxin (substance)
SNOMED CT
373534001
UMLS CUI
C0012258
RxNorm CUI
3403

Clinical Data

This intervention maps to 21 entities in the Healos knowledge graph.

6
Conditions
7
Biomarkers
4
Specialists
0
Symptoms
16
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.