Substance / Medication

Digoxin

Overview

Active Ingredient
digoxin
RxNorm CUI
3407
Labeler: A-S Medication SolutionsUpdated: 2026-02-14T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Digoxin tablets are contraindicated in patients with: Warnings and Precautions (5.1) [see] Ventricular fibrillation Known hypersensitivity to digoxin (reactions seen include unexplained rash, swelling of the mouth, lips or throat or a difficulty in breathing). A hypersensitivity reaction to other di

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

12 trials linked to this intervention

12
Total Trials
3
Recruiting
3
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Expert Consensus on the Diagnosis and Management of Digoxin Toxicity.
Hack Jason B, Wingate Sue, Zolty Ron et al. · Am J Med · 2025
PMID: 39265879Meta-Analysis
From Salvador Dali and Von Gogh to BRASH: a case-based systematic literature review of digoxin induced BRASH syndrome.
Zaman Muhammad Adnan, Milton Karly, Korani Warsha et al. · Future Cardiol · 2025
PMID: 39953848Meta-AnalysisFull text (PMC)
Digoxin and Outcomes in Patients with Heart Failure and Preserved Ejection Fraction (HFpEF) Patients: A Systematic Review and Meta- Analysis.
Hashemi-Shahri Seyed H, Aghajanloo Ali, Ghavami Vahid et al. · Curr Drug Targets · 2023
PMID: 36065922Meta-Analysis
Chemotherapy-induced cardiotoxicity: a new perspective on the role of Digoxin, ATG7 activators, Resveratrol, and herbal drugs.
Al-Hussaniy Hany Akeel, Alburghaif Ali Hikmat, Alkhafaje Zahraa et al. · J Med Life · 2023
PMID: 37305823Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Digoxin (substance)
SNOMED CT
387461009
UMLS CUI
C0012265
RxNorm CUI
3407
Labeler
A-S Medication Solutions

Clinical Data

This intervention maps to 21 entities in the Healos knowledge graph.

6
Conditions
7
Biomarkers
4
Specialists
0
Symptoms
12
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.