Substance / Medication

Duloxetine

Overview

Active Ingredient
duloxetine
RxNorm CUI
72625

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Research Evidence

Published studies and systematic reviews

Sort:
Efficacy of Duloxetine for Postspine Surgery Pain: A Systematic Review and Meta-Analysis.
Aleid Abdulsalam Mohammed, Alshehri Faisal, Alasiri Naif et al. · Brain Behav · 2025
PMID: 39740780Meta-AnalysisFull text (PMC)
Efficacy and safety of preoperative duloxetine in reducing post-laparoscopic surgery pain: a meta-analysis of randomized placebo-controlled trials.
Barbosa Eduardo Cerchi, Ortegal Guilherme Henrique Pires Carvalho, de Andrade Lucas Santos et al. · Int J Clin Pharm · 2025
PMID: 39812914Meta-Analysis
Incomplete reporting of adverse events in duloxetine trials: a meta-research survey of randomized controlled trials vs placebo.
Rolland P, Jutel A, Douget Le et al. · J Clin Epidemiol · 2025
PMID: 39826626Meta-Analysis
Perioperative Duloxetine in Total Joint Arthroplasty: An Umbrella Review.
Tian Xiaomeng, Wang Wenchao, Xu Ying et al. · J Perianesth Nurs · 2025
PMID: 39520423Meta-Analysis
Efficacy of duloxetine in treating temporomandibular joint disorder: a systematic review with bayesian meta-analysis.
Sivakumar Sasidharan, Sundramoorthy Ashok K, Narayanan Sankar et al. · BMC Oral Health · 2025
PMID: 40775766Meta-AnalysisFull text (PMC)
Duloxetine reduces opioid consumption and pain after total hip or knee arthroplasty: a meta-analysis of randomized controlled trials.
Lin Yicai, Jiang Mingyang, Liao Chun et al. · J Orthop Surg Res · 2024
PMID: 38481321Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Duloxetine (substance)
SNOMED CT
407032004
UMLS CUI
C0245561
RxNorm CUI
72625

Clinical Data

This intervention maps to 8 entities in the Healos knowledge graph.

3
Conditions
1
Biomarkers
2
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.