Substance / Medication

Estrogen receptor agonist

Overview

Active Ingredient
estrogens
RxNorm CUI
4100

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

78 trials linked to this intervention

78
Total Trials
14
Recruiting
23
With Results

Research Evidence

Published studies and systematic reviews

Sort:
GPR30 estrogen receptor agonists induce mechanical hyperalgesia in the rat.
Kuhn Julia, Dina Olayinka A, Goswami Chandan et al. · Eur J Neurosci · 2008
PMID: 18371086Observational
Effects of selective estrogen receptor agonists on food intake and body weight gain in rats.
Roesch Darren M · Physiol Behav · 2006
PMID: 16181647Observational
Effect of estrogen receptor agonists treatment in MPTP mice: evidence of neuroprotection by an ER alpha agonist.
D'Astous Myreille, Morissette Marc, Di Paolo Thérèse · Neuropharmacology · 2004
PMID: 15567427Observational
Review of current and emerging estrogen receptor agonists for vaginal atrophy.
Donders Gilbert G G, Akinosoglou Karolina, Massie Zoë et al. · Expert Opin Pharmacother · 2025
PMID: 39772973Review
FT-GNN Tool for Bridging HRMS Features and Bioactivity: Uncovering Unidentified Estrogen Receptor Agonists in Sewage.
Fan Fan, Liu Fu, Yu Qingmiao et al. · Environ Sci Technol · 2025
PMID: 40201978Other
Predicting estrogen receptor agonists from plastic additives across various aquatic-related species using machine learning and AlphaFold2.
Shi Wen-Jun, Cao Zhou, Long Xiao-Bing et al. · J Hazard Mater · 2025
PMID: 40378742Preclinical
The elucidation of species-specific receptor pharmacology: A case study using subtype-selective para- and meta-carborane estrogen receptor agonists.
Adeluola Adeoluwa A, Radomska Hanna S, Wilson Tyler A et al. · J Pharmacol Exp Ther · 2025
PMID: 39892992Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Substance with estrogen receptor agonist mechanism of action (substance)
SNOMED CT
1052201004
UMLS CUI
C0014939
RxNorm CUI
4100

Clinical Data

This intervention maps to 13 entities in the Healos knowledge graph.

7
Conditions
3
Biomarkers
2
Specialists
0
Symptoms
78
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.