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Substance / Medication

Human chorionic gonadotropin

SNOMED 59433001 UMLS C1141639

Overview

Active Ingredient

chorionic gonadotropin

RxNorm CUI

4986

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Female infertility

Undescended testicle

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

LOINC 3016-3

secondary

LOINC 2243-4

primary

LOINC 2986-8

primary

Clinical Trials

54 trials linked to this intervention

54

Total Trials

7

Recruiting

16

With Results

Recent Trials

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Effect of Androgel on Type 2 Diabetic Males With Hypogonadism

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The Therapy of Nebido as Mono or in Combination With PDE-5 Inhibitors in Hypogonadal Patients With Erectile Dysfunction

NCT00421460Phase 4Completed30 enrolled

View all 54 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:

Translational interdisciplinary research on human chorionic gonadotropin's enhancement of neuroendocrine crosstalk: a novel medical hypothesis for systemic adjunctive treatment of psychiatric disorders.

Gaspary João Francisco Pollo, Lopes Luis Felipe Dias, Camara Antonio Geraldo · Front Psychiatry · 2025

PMID: 40365004Meta-AnalysisFull text (PMC)

The association between human chorionic gonadotropin and adverse pregnancy outcomes: a systematic review and meta-analysis.

Peris Monique, Crompton Kylie, Shepherd Daisy A et al. · Am J Obstet Gynecol · 2024

PMID: 37572838Meta-Analysis

Dual trigger improves the pregnancy rate in fresh in vitro fertilization (IVF) cycles compared with the human chorionic gonadotropin (hCG) trigger: a systematic review and meta-analysis of randomized trials.

Hsia Li-Hsin, Lee Tsung-Hsien, Lin Yu-Hsuan et al. · J Assist Reprod Genet · 2023

PMID: 37466846Meta-AnalysisFull text (PMC)

Intrauterine Insemination After Human Chorionic Gonadotropin Trigger or Luteinizing Hormone Surge: A Meta-analysis.

Potapragada Nivedita R, Babayev Elnur, Strom Danielle et al. · Obstet Gynecol · 2023

PMID: 37290111Meta-Analysis

Intrauterine instillation of human chorionic gonadotropin at the time of blastocyst transfer: Systematic review and meta-analysis.

Murugesu Sughashini, Theodorou Efstathios, Kasaven Lorraine S et al. · J Gynecol Obstet Hum Reprod · 2023

PMID: 37666360Meta-Analysis

Association between human chorionic gonadotropin (hCG) levels and adverse pregnancy outcomes: A systematic review and meta-analysis.

Skogler Johannes, Moberg Tilda, Tancredi Luca et al. · Pregnancy Hypertens · 2023

PMID: 37951184Meta-Analysis

The Effect of Serum-Human Chorionic Gonadotropin on Pregnancy Complications and Adverse Pregnancy Outcomes: A Systematic Review and Meta-Analysis.

Huang Ju, Liu Yuying, Yang Hua et al. · Comput Math Methods Med · 2022

PMID: 36118828Meta-AnalysisFull text (PMC)

Second trimester maternal serum D-dimer combined with alpha-fetoprotein and free β-subunit of human chorionic gonadotropin predict hypertensive disorders of pregnancy: a systematic review and retrospective case-control study.

Chen Yiming, Chen Yijie, Wang Xue et al. · J Transl Med · 2021

PMID: 33653375Meta-AnalysisFull text (PMC)

Intrauterine administration of peripheral blood mononuclear cells activated by human chorionic gonadotropin in patients with repeated implantation failure: A meta-analysis.

Qin Qi, Chang Hong, Zhou Shuling et al. · J Reprod Immunol · 2021

PMID: 33878637Meta-Analysis

Association of pregnancy per artificial insemination with gonadotropin-releasing hormone and human chorionic gonadotropin administered during the luteal phase after artificial insemination in dairy cows: A meta-analysis.

Besbaci M, Abdelli A, Minviel J J et al. · J Dairy Sci · 2020

PMID: 31785879Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Endocrinology, Diabetes & Metabolism Physician

Internal Medicine — Endocrinology, Diabetes & Metabolism

NUCC 207RE0101X

Obstetrics & Gynecology Physician

Obstetrics & Gynecology

NUCC 207V00000X

Reproductive Endocrinology Physician

Obstetrics & Gynecology — Reproductive Endocrinology

NUCC 207VE0102X

Urology Physician

Urology

NUCC 208800000X

Find a Provider

Health Goals

Goals connected through associated conditions

Balance Hormones Support Reproductive Health

Quick Facts

Type: Substance / Medication
Fully Specified Name: Human chorionic gonadotropin (substance)
SNOMED CT: 59433001
UMLS CUI: C1141639
RxNorm CUI: 4986

Clinical Data

This intervention maps to 12 entities in the Healos knowledge graph.

3

Conditions

3

Biomarkers

4

Specialists

0

Symptoms

54

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.