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Substance / Medication

Hydrocortisone acetate

SNOMED 79380007UMLS C0063077

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Shock
Contact dermatitis
Colitis gravis
Hemorrhoids
Pruritus ani
Congenital adrenal hyperplasia
Hypoadrenalism
Adrenal cortical hypofunction
Rheumatism
Dermatosis of scalp
Acute severe exacerbation of asthma

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Eosinophils

LOINC 711-2

secondary

IgE

LOINC 19113-0

secondary

Potassium

LOINC 2823-3

secondary

Cortisol

LOINC 2143-6

primary

Clinical Trials

1 trials linked to this intervention

1
Total Trials
1
Recruiting
0
With Results

Recent Trials

Sore Throat After Open Neck Elective Surgery

NCT07124650Phase 4Recruiting764 enrolled
View all 1 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:
UTILIZATION OF HYDROCORTISONE ACETATE PHONOPHORESIS IN COMBINATION WITH THERAPEUTIC EXERCISE IN THE REHABILITATION MANAGEMENT OF FUNCTIONAL LIMITATIONS CAUSED BY KNEE ARTHROFIBROSIS.
Akhalkatsi V, Matiashvili M, Maskhulia L et al. · Georgian Med News · 2021
PMID: 35000914RCT
Efficacy of hydrocortisone acetate/hyaluronidase vs triamcinolone acetonide/hyaluronidase in the treatment of oral submucous fibrosis.
Singh Mangal, Niranjan H S, Mehrotra Ravi et al. · Indian J Med Res · 2010
PMID: 20516538RCT
Topical treatment of acute otitis externa: clinical comparison of an antibiotics ointment alone or in combination with hydrocortisone acetate.
Mösges Ralph, Domröse Christian M, Löffler Jürgen · Eur Arch Otorhinolaryngol · 2007
PMID: 17503066RCT
1% hydrocortisone ointment is an effective treatment of pruritus ani: a pilot randomized controlled crossover trial.
Al-Ghnaniem R, Short K, Pullen A et al. · Int J Colorectal Dis · 2007
PMID: 17534634RCT
Pimecrolimus cream, 1%, vs hydrocortisone acetate cream, 1%, in the treatment of facial seborrheic dermatitis: a randomized, investigator-blind, clinical trial.
Firooz Alireza, Solhpour Amirreza, Gorouhi Farzam et al. · Arch Dermatol · 2006
PMID: 16924062RCT
Anal Albendazole application for pruritus ani in threadworm infestation.
Singh Shivaram Prasad, Panda Chittaranjan, Rout Niranjan et al. · J Trop Pediatr · 2005
PMID: 15958409RCT
0.03% Tacrolimus ointment applied once or twice daily is more efficacious than 1% hydrocortisone acetate in children with moderate to severe atopic dermatitis: results of a randomized double-blind controlled trial.
Reitamo S, Harper J, Bos J D et al. · Br J Dermatol · 2004
PMID: 15030341Trial
Budesonide foam vs. hydrocortisone acetate foam in the treatment of active ulcerative proctosigmoiditis.
Bar-Meir Simon, Fidder Herma H, Faszczyk Mark et al. · Dis Colon Rectum · 2003
PMID: 12847368Trial
Efficacy and safety of tacrolimus ointment compared with that of hydrocortisone acetate ointment in children with atopic dermatitis.
Reitamo Sakari, Van Leent Edwin J M, Ho Vincent et al. · J Allergy Clin Immunol · 2002
PMID: 11898004Trial
Pharmacokinetics and rectal bioavailability of hydrocortisone acetate after single and multiple administration in healthy subjects and patients.
Tromm A, Möllmann H, Barth J et al. · J Clin Pharmacol · 2001
PMID: 11361050Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Dermatology Physician

Dermatology

NUCC 207N00000X
Internal Medicine Physician

Internal Medicine

NUCC 207R00000X
Allergy & Immunology (Internal Medicine) Physician

Internal Medicine — Allergy & Immunology

NUCC 207RA0201X
Endocrinology, Diabetes & Metabolism Physician

Internal Medicine — Endocrinology, Diabetes & Metabolism

NUCC 207RE0101X
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Health Goals

Goals connected through associated conditions

Balance HormonesPromote Skin Health

Quick Facts

Type
Substance / Medication
Fully Specified Name
Hydrocortisone acetate (substance)
SNOMED CT
79380007
UMLS CUI
C0063077

Clinical Data

This intervention maps to 21 entities in the Ltrl knowledge graph.

11
Conditions
4
Biomarkers
4
Specialists
0
Symptoms
1
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.