Substance / Medication

Methylprednisolone sodium succinate

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Calcidiol+ercalcidiol

LOINC 14635-7

secondary

Cobalamins

LOINC 2132-9

secondary

Leukocytes

LOINC 26464-8

secondary

Complement C3c

LOINC 4485-9

primary

Eosinophils

LOINC 711-2

primary

IgE

LOINC 19113-0

primary

Nuclear Ab

LOINC 8061-4

primary

Clinical Trials

464 trials linked to this intervention

464

Total Trials

Recruiting

138

With Results

Recent Trials

Immune Regulation in Ulcerative Colitis or Crohn s Disease

NCT00001184Recruiting1000 enrolled

Activation and Function of Eosinophils in Conditions With Blood or Tissue Eosinophilia

NCT00001406Recruiting800 enrolled

Role of Genetic Factors in the Development of Lung Disease

NCT00001532Recruiting3500 enrolled

Sample Collections From the Airways of Asthmatic Patients

NCT00001888Completed574 enrolled

Study of ONTAK (Denileukin Diftitox) in Cutaneous T-Cell Lymphoma (CTCL) Patients

NCT00050999Phase 4Completed195 enrolled

View all 464 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:

A systematic review of validated methods for identifying erythema multiforme major/minor/not otherwise specified, Stevens-Johnson Syndrome, or toxic epidermal necrolysis using administrative and claims data.

Schneider Gary, Kachroo Sumesh, Jones Natalie et al. · Pharmacoepidemiol Drug Saf · 2012

PMID: 22262611Meta-Analysis

Efficacy of methylprednisolone sodium succinate combined with acoustic resonance therapy on inflammatory response indicators and cerebral microcirculation in patients with sudden sensorineural hearing loss.

Qin Jiangyuan, Huang Geng, Lin Xiaoyu et al. · Eur J Med Res · 2025

PMID: 40604846RCTFull text (PMC)

[Application of Methylprednisolone Sodium Succinate Combined with Tropisetron in Prevention of Nausea and Vomiting under Microvascular Decompression of Hemifacial Spasm].

Wang Dong Liang, Song Hai Dong, Hao Qing Pei et al. · Zhongguo Yi Xue Ke Xue Yuan Xue Bao · 2021

PMID: 33663659RCT

Methylprednisolone sodium succinate reduces spinal cord swelling but does not affect recovery of dogs with surgically treated thoracolumbar intervertebral disk herniation.

Nishida Hidetaka, Tanaka Hiroshi, Kitamura Masahiko et al. · Jpn J Vet Res · 2016

PMID: 29786990RCT

[Clinical effect of methylprednisolone sodium succinate and mouse nerve growth factor for injection in treating acute spinal cord injury and cauda equina injury].

Zeng Yun, Xiong Min, Yu Hualong et al. · Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi · 2010

PMID: 21049601RCT

[Observation on therapeutic effect of He's Santong needling methods on cold erythema multiforme].

Li He · Zhongguo Zhen Jiu · 2009

PMID: 19873917RCT

Plasmapheresis and RATG-induced serum sickness.

Christiaans Maarten H L, van Hooff Johannes P · Transplantation · 2006

PMID: 16436978RCT

Identification of HLA-DRPhebeta47 as the susceptibility marker of hypersensitivity to beryllium in individuals lacking the berylliosis-associated supratypic marker HLA-DPGlubeta69.

Amicosante Massimo, Berretta Floriana, Rossman Milton et al. · Respir Res · 2005

PMID: 16098233RCTFull text (PMC)

Does high dose methylprednisolone sodium succinate really improve neurological status in patient with acute cervical cord injury?: a prospective study about neurological recovery and early complications.

Ito Yasuo, Sugimoto Yoshihisa, Tomioka Masao et al. · Spine (Phila Pa 1976) · 2009

PMID: 19713878Trial

Early complications of high-dose methylprednisolone sodium succinate treatment in the follow-up of acute cervical spinal cord injury.

Matsumoto T, Tamaki T, Kawakami M et al. · Spine (Phila Pa 1976) · 2001

PMID: 11224891Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Dermatology Physician

Dermatology

NUCC 207N00000X

Allergy & Immunology (Internal Medicine) Physician

Internal Medicine — Allergy & Immunology

NUCC 207RA0201X

Nephrology Physician

Internal Medicine — Nephrology

NUCC 207RN0300X

Pulmonary Disease Physician

Internal Medicine — Pulmonary Disease

NUCC 207RP1001X

Rheumatology Physician

Internal Medicine — Rheumatology

NUCC 207RR0500X

Neurology Physician

Psychiatry & Neurology — Neurology

NUCC 2084N0400X

Find a Provider

Health Goals

Goals connected through associated conditions

Manage Autoimmune Risk Promote Skin Health Support Respiratory Health

Quick Facts

Type: Substance / Medication
Fully Specified Name: Methylprednisolone sodium succinate (substance)
SNOMED CT: 412248005
UMLS CUI: C0700546

Clinical Data

This intervention maps to 36 entities in the Ltrl knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

464

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.