Nuclear Ab

OtherAlso known as: ANA CSF Ql HEp2 substAlso known as: ANA CSF Ql IFAlso known as: ANA Fld IF-aCnc

Detects antibodies targeting cell nuclei using specialized immunological techniques.

Normal Range

0 – 1

Abnormal Levels

< 0

> 1

Specimen Type

Blood

Why This Biomarker Matters

Nuclear antibodies are key indicators of autoimmune disease. Positive results help diagnose conditions requiring specific treatment to prevent joint, organ, and tissue damage.

Optimal Ranges

Clinician-defined 4-point reference thresholds

Default Range

Low

Borderline Low

Optimal

Borderline High

Overview

Nuclear antibodies are proteins your immune system produces that attack the nucleus of your own cells. This test uses immunofluorescence to detect and measure these antibodies in synovial fluid (joint fluid). Elevated levels are commonly associated with autoimmune diseases like lupus, rheumatoid arthritis, and Sjögren's syndrome. A positive result suggests the immune system is attacking the body's own cells.

Related Health Conditions

Conditions where Nuclear Ab is commonly tested

Autoimmune disease

Systemic lupus erythematosus

Related Health Goals

Manage Autoimmune Risk

Treatments & Interventions

Therapies monitored using Nuclear Ab

Hydroxychloroquine sulfate

Cortisone

Azathioprine sodium

Methylprednisolone acetate

Prednisolone acetate

Prednisolone sodium phosphate

Prednisolone tertiary butylacetate

Dexamethasone acetate

Methylprednisolone

Triamcinolone

Triamcinolone diacetate

Prednisolone

Prednisone

Cortisone acetate

Azathioprine

Technical Information (LOINC Codes)

Standardized laboratory codes for this biomarker

8061-4Primary

Nuclear Ab [Presence] in Serum

47383-5

Nuclear Ab [Presence] in Serum by Immunoassay

29953-7

Nuclear Ab [Titer] in Serum

{titer}

5048-4

Nuclear Ab [Titer] in Serum by Immunofluorescence

{titer}

27200-5

Nuclear Ab [Units/volume] in Serum

[arb'U]/mL

5047-6

Nuclear Ab [Units/volume] in Serum by Immunoassay

[IU]/mL

6822-1

Nuclear Ab [Titer] in Synovial fluid by Immunofluorescence

{titer}

21423-9

Nuclear Ab [Titer] in Serum by Immunofluorescence (IF) rat liver

{titer}

14613-4

Nuclear Ab [Titer] in Body fluid

{titer}

40655-3

Nuclear Ab [Titer] in Serum by Immunoassay

{titer}

16392-3

Nuclear Ab [Presence] in Serum by Rodent substrate

14607-6

Nuclear Ab [Presence] in Body fluid

59069-5

Nuclear Ab [Presence] in Serum by Hep2 substrate

9423-5

Nuclear Ab [Units/volume] in Serum by Immunofluorescence

[IU]/mL

33253-6

Nuclear Ab [Titer] in Serum by Hep2 substrate

{titer}

44751-6

Nuclear Ab [Presence] in Serum by Immunofluorescence (IF) rat kidney

42254-3

Nuclear Ab [Presence] in Serum by Immunofluorescence

31541-6

Nuclear Ab [Units/volume] in Pericardial fluid

[arb'U]/mL

31542-4

Nuclear Ab [Units/volume] in Pleural fluid

[arb'U]/mL

31543-2

Nuclear Ab [Units/volume] in Peritoneal fluid

[arb'U]/mL

31544-0

Nuclear Ab [Units/volume] in Synovial fluid

[arb'U]/mL

31540-8

Nuclear Ab [Units/volume] in Body fluid

[arb'U]/mL

16394-9

Nuclear Ab [Presence] in Body fluid by Immunofluorescence

13066-6

Nuclear Ab [Units/volume] in Body fluid by Immunofluorescence

[arb'U]/mL

16393-1

Nuclear Ab [Units/volume] in Serum by Rodent substrate

[arb'U]/mL

44752-4

Nuclear Ab [Units/volume] in Serum by Immunofluorescence (IF) rat kidney

[arb'U]/mL

14616-7

Nuclear Ab [Titer] in Synovial fluid

{titer}

14615-9

Nuclear Ab [Titer] in Peritoneal fluid

{titer}

14614-2

Nuclear Ab [Titer] in Pleural fluid

{titer}

57010-1

Nuclear Ab [Presence] in Pleural fluid by Immunoassay

14612-6

Nuclear Ab [Titer] in Pericardial fluid

{titer}

63294-3

Nuclear Ab [Presence] in Cerebral spinal fluid by Immunofluorescence

63295-0

Nuclear Ab [Presence] in Cerebral spinal fluid by Hep2 substrate

63296-8

Nuclear Ab [Titer] in Cerebral spinal fluid by Immunofluorescence

{titer}

63297-6

Nuclear Ab [Titer] in Cerebral spinal fluid by Hep2 substrate

{titer}

14610-0

Nuclear Ab [Presence] in Synovial fluid

68369-8

Nuclear Ab [Presence] in Pericardial fluid by Immunofluorescence

68370-6

Nuclear Ab [Presence] in Pleural fluid by Immunofluorescence

68371-4

Nuclear Ab [Presence] in Peritoneal fluid by Immunofluorescence

68372-2

Nuclear Ab [Presence] in Synovial fluid by Immunofluorescence

68373-0

Nuclear Ab [Titer] in Pericardial fluid by Immunofluorescence

{titer}

68374-8

Nuclear Ab [Titer] in Pleural fluid by Immunofluorescence

{titer}

68375-5

Nuclear Ab [Titer] in Peritoneal fluid by Immunofluorescence

{titer}

68376-3

Nuclear Ab [Titer] in Body fluid by Immunofluorescence

{titer}

14609-2

Nuclear Ab [Presence] in Peritoneal fluid

14608-4

Nuclear Ab [Presence] in Pleural fluid

Available Lab Tests

Order tests that measure this biomarker

ana screen ifa with reflex to titer and pattern

$59.79

rheumatoid arthritis basic plus

$131.74

Find Specialists

Doctors who commonly order this test

Allergy & Immunology

Nephrology

Rheumatology