Substance / Medication

Prednisolone

Overview

Active Ingredient
prednisolone
RxNorm CUI
8638

Indications

Prednisolone Oral Solution USP is indicated in the following conditions: 1. Endocrine Disorders Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the first choice: synthetic analogs may be used in conjunction with mineralocorticoids where applicable: in infancy mineralocorticoid supplementation is of particular importance). Congenital adrenal hyperplasia Nonsuppurative thyroiditis Hypercalcemia associated with cancer 2. Rheumatic Disorders As adjunctive therapy fo

Labeler: A-S Medication SolutionsUpdated: 2026-01-23T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Systemic fungal infections.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

102 trials linked to this intervention

102
Total Trials
36
Recruiting
19
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Efficacy and safety of various Intravenous Methylprednisolone regimens in Moderate to Severe Thyroid Eye Disease: A systematic review.
Aishwarya Ankita, Shrivastava Divanshi, Singh Adarsh Kumar et al. · Indian J Ophthalmol · 2025
PMID: 40719710Meta-AnalysisFull text (PMC)
The use of methylprednisolone after third molar surgery. A systematic review and meta-analysis of randomized controlled trials.
Libório H, Borges T, Pereira M et al. · Med Oral Patol Oral Cir Bucal · 2025
PMID: 39724528Meta-AnalysisFull text (PMC)
Adrenocorticotropic Hormone versus Prednisolone for Infantile Epileptic Spasms Syndrome: A Systematic Review and Economic Evaluation.
Gao Ruonan, Cheng Xiao, Huang Liang et al. · Neuropediatrics · 2025
PMID: 39900086Meta-Analysis
The role of methylprednisolone in severe COVID-19 patients: a meta-analysis.
Xu Wanru, Zeng Yujun, Han Hedong et al. · Front Med (Lausanne) · 2024
PMID: 39185470Meta-AnalysisFull text (PMC)
Highlighting inaccurate data supporting prednisolone administration in recurrent pregnancy loss: Comments on frequently cited meta-analysis.
Béquet Y L B N, van der Hoorn M L P, Lashley E E L O · Am J Reprod Immunol · 2024
PMID: 38414234Meta-Analysis
The Efficacy, Adverse Effects and Economic Implications of Oral Versus Intravenous Methylprednisolone for the Treatment of Optic Neuritis: A Systematic Review.
Pietris James, Lam Antoinette, Bacchi Stephen et al. · Semin Ophthalmol · 2024
PMID: 38013424Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Prednisolone (substance)
SNOMED CT
116601002
UMLS CUI
C0032950
RxNorm CUI
8638
Labeler
A-S Medication Solutions

Clinical Data

This intervention maps to 34 entities in the Healos knowledge graph.

20
Conditions
7
Biomarkers
5
Specialists
0
Symptoms
102
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.