Substance / Medication

Oxazepam

Overview

Active Ingredient
oxazepam
RxNorm CUI
7781

Indications

Oxazepam capsules are indicated for the management of anxiety disorders or for the short-term relief of the symptoms of anxiety. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic. Anxiety associated with depression is also responsive to oxazepam therapy. This product has been found particularly useful in the management of anxiety, tension, agitation and irritability in older patients. Alcoholics with acute tremulousness, inebriat

Labeler: Leading Pharma, LLCUpdated: 2025-07-11T00:00:00.000ZFull label on DailyMed

Boxed Warning

FDA Black Box Warning

WARNING: RISKS FROM CONCOMITANT USE WITH OPIOIDS; ABUSE, MISUSE, AND ADDICTION; and DEPENDENCE AND WITHDRAWAL REACTIONS Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death. Reserve concomitant prescribing of these drugs for use in

Contraindications

When this intervention should not be used

History of previous hypersensitivity reaction to oxazepam. Oxazepam is not Indicated in psychoses.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

1 trials linked to this intervention

1
Total Trials
0
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Oxazepam and cognitive reappraisal: A randomised experiment.
Nilsonne Gustav, Tamm Sandra, Golkar Armita et al. · PLoS One · 2021
PMID: 33886568RCTFull text (PMC)
Comparing the effects of oxazepam and diazepam in actual highway driving and neurocognitive test performance: a validation study.
Jongen S, Vuurman E F P M, Ramaekers J G et al. · Psychopharmacology (Berl) · 2018
PMID: 29500585RCTFull text (PMC)
Effects of the combination of metyrapone and oxazepam on cocaine craving and cocaine taking: a double-blind, randomized, placebo-controlled pilot study.
Kablinger Anita S, Lindner Marie A, Casso Stephanie et al. · J Psychopharmacol · 2012
PMID: 22236504RCT
Effects of oxazepam on affective perception, recognition, and event-related potentials.
Olofsson Jonas K, Gospic Katarina, Petrovic Predrag et al. · Psychopharmacology (Berl) · 2011
PMID: 21197615RCT
Lack of sedative effects after vespertine intake of oxazepam as hypnotic in healthy volunteers.
Wilhelm Barbara, Kellert Renate, Schnell Rainer et al. · Psychopharmacology (Berl) · 2009
PMID: 19551373RCT
Oxazepam does not modulate the behavioral effects of d-amphetamine in humans.
Lile Joshua A, Stoops William W, Wagner Frances P et al. · Pharmacol Biochem Behav · 2005
PMID: 16182353RCT
[Treatment of Alcohol Withdrawal Syndrome with Oxazepam or Clomethiazole - A Naturalistic Observational Study].
Verthein Uwe, Kuhn Silke, Gabriel Katrin et al. · Psychiatr Prax · 2018
PMID: 28371954Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Oxazepam (substance)
SNOMED CT
387455006
UMLS CUI
C0029997
RxNorm CUI
7781
Labeler
Leading Pharma, LLC

Clinical Data

This intervention maps to 8 entities in the Healos knowledge graph.

3
Conditions
1
Biomarkers
2
Specialists
0
Symptoms
1
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.