Substance / Medication

Phenylpropanolamine

Overview

Active Ingredient
phenylpropanolamine
RxNorm CUI
8175

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

426 trials linked to this intervention

426
Total Trials
122
Recruiting
109
With Results

Research Evidence

Published studies and systematic reviews

Sort:
The impact of oral phenylpropanolamine on blood pressure: a meta-analysis and review of the literature.
Salerno S M, Jackson J L, Berbano E P · J Hum Hypertens · 2005
PMID: 15944721Meta-Analysis
Urodynamic and haemodynamic effects of a single oral administration of ephedrine or phenylpropanolamine in continent female dogs.
Noël Stéphanie, Massart Laurent, Hamaide Annick · Vet J · 2012
PMID: 21715199Observational
[Stroke and phenylpropanolamine: what risk factors and what recommendations in request?].
Die-Kacou H, Kamagaté M, Daubrey-Potey T H et al. · Dakar Med · 2007
PMID: 19102094Observational
Phenylpropanolamine contained in cold remedies and risk of hemorrhagic stroke.
Yoon B W, Bae H J, Hong K S et al. · Neurology · 2007
PMID: 17210897Observational
Phenylpropanolamine constricts mouse and human blood vessels by preferentially activating alpha2-adrenoceptors.
Flavahan Nicholas A · J Pharmacol Exp Ther · 2005
PMID: 15608085Observational
Pharmacokinetic interactions between phenylpropanolamine, caffeine and chlorpheniramine in rats.
Kaddoumi Amal, Nakashima Mihoko N, Wada Mitsuhiro et al. · Eur J Pharm Sci · 2004
PMID: 15158906Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Phenylpropanolamine (substance)
SNOMED CT
387464001
UMLS CUI
C0031495
RxNorm CUI
8175

Clinical Data

This intervention maps to 11 entities in the Healos knowledge graph.

3
Conditions
3
Biomarkers
3
Specialists
0
Symptoms
426
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.