Treatments & Interventions
Clinical Trials
75
Total Trials
17
Recruiting
29
With Results
Recent Trials
Role of Genetic Factors in the Development of Lung Disease
NCT00001532Recruiting3,500 enrolled
Natural History of Bronchiectasis
NCT00943514Recruiting900 enrolled
Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study
NCT05548283Phase 4Recruiting730 enrolled
Modulate-CF: Cystic Fibrosis Transmembrane Regulator (CFTR) Biomarker Study to Evaluate the Rescue of Mutant CFTR in Patients With Cystic Fibrosis Treated With CFTR-modulators
NCT04732910Recruiting500 enrolled
A Cohort for Inflammatory Respiratory Diseases: From Phenotyping to Personalised Medicine
NCT07274631Recruiting470 enrolled
Research Evidence
Peer-reviewed studies linked via MeSH term "Fibrosis, Cystic" from the MEDLINE/PubMed database.
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Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis.
[object Object], [object Object], [object Object] et al. · Cochrane Database Syst Rev · 2025
Tools used to measure quality of life in adults with cystic fibrosis- a systematic review.
[object Object], [object Object], [object Object] et al. · Health Qual Life Outcomes · 2025
Reproductive decision-making of people living with cystic fibrosis and their partners: A systematic review of psychosocial and ethical considerations.
[object Object], [object Object] · Patient Educ Couns · 2025
PMID: 39306878Meta-Analysis
Functional variants in the cystic fibrosis transmembrane conductance regulator (CFTR) gene are associated with increased risk of colorectal cancer.
[object Object], [object Object], [object Object] et al. · Hum Mol Genet · 2025
Unlocking the potential of CRISPR-Cas9 for cystic fibrosis: A systematic literature review.
[object Object], [object Object] · Gene · 2025
PMID: 39832688Meta-Analysis
Otolaryngological manifestations of cystic fibrosis in children: A systematic review.
[object Object], [object Object], [object Object] et al. · Int J Pediatr Otorhinolaryngol · 2025
PMID: 39879870Meta-Analysis
Infection prevention and control in cystic fibrosis: An update of a systematic review of interventions.
[object Object], [object Object], [object Object] et al. · J Cyst Fibros · 2025
PMID: 39198075Meta-Analysis
Clinical Efficacy and Safety of Treatments for Exocrine Pancreatic Insufficiency: A Systematic Literature Review.
[object Object], [object Object], [object Object] et al. · Digestion · 2025
Measurement of treatment burden in cystic fibrosis: A systematic review.
[object Object], [object Object], [object Object] et al. · J Cyst Fibros · 2025
PMID: 39616120Meta-Analysis
Evaluation of clinical practice guidelines on treatment of cystic fibrosis: A systematic review.
[object Object], [object Object], [object Object] et al. · J Cyst Fibros · 2025
PMID: 39956717Meta-Analysis
Search all PubMed articles for Cystic fibrosis
Research data from MEDLINE/PubMed
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Absent ductus deferens
Very frequent (80-99%)HP:0012873
Bronchiectasis
Very frequent (80-99%)HP:0002110
Elevated sweat chloride
Very frequent (80-99%)HP:0012236
Intestinal malabsorption
Very frequent (80-99%)HP:0002024
Pancreatic insufficiency
Very frequent (80-99%)HP:0001738
Pulmonary obstruction
Very frequent (80-99%)HP:0006536
respiratory infections, recurrent
Very frequent (80-99%)HP:0002205
Chronic sinus disease
Frequent (30-79%)HP:0011109
Clubbing of fingers
Frequent (30-79%)HP:0100759
Decreased FEF25-75%
Frequent (30-79%)HP:0032359
Male infertility
Frequent (30-79%)HP:0003251
Pulmonary infections
Frequent (30-79%)HP:0006532
Salty tasting skin
Frequent (30-79%)HP:6000725
Undergrowth
Frequent (30-79%)HP:0001508
Bronchial asthma
Occasional (5-29%)HP:0002099
Cor pulmonale
Occasional (5-29%)HP:0001648
Decreased BMI
Occasional (5-29%)HP:0045082
Dehydration
Occasional (5-29%)HP:0001944
Depressive episode
Occasional (5-29%)HP:0000716
Diarrhea
Occasional (5-29%)HP:0002014
Distal intestinal obstruction syndrome
Occasional (5-29%)HP:0004401
Elevated liver enzymes
Occasional (5-29%)HP:0002910
Excessive, persistent worry and fear
Occasional (5-29%)HP:0000739
Fat in feces
Occasional (5-29%)HP:0002570
Gastroesophageal reflux disease
Occasional (5-29%)HP:0002020
Liver disease
Occasional (5-29%)HP:0001392
Lower respiratory tract infections
Occasional (5-29%)HP:0002783
Osteopenia
Occasional (5-29%)HP:0000938
Pancreatitis
Occasional (5-29%)HP:0001733
Rectum protrudes through anus
Occasional (5-29%)HP:0002035
Related Conditions
Cystic fibrosis without meconium ileus(child)
Cystic fibrosis with meconium ileus(child)
Cystic fibrosis of the lung(child)
Follicular hamartoma with alopecia and cystic fibrosis syndrome(child)
Cystic fibrosis of pancreas(child)
Cystic fibrosis with gastritis and megaloblastic anemia syndrome(child)
Fetal cystic fibrosis(child)
Classical cystic fibrosis(child)
Atypical cystic fibrosis(child)
Subclinical cystic fibrosis(child)
Cystic fibrosis due to heterozygous deltaF508 mutation(child)
Cystic fibrosis due to homozygous deltaF508 mutation(child)
Diabetes mellitus due to cystic fibrosis(child)
Inherited mucociliary clearance defect(parent)
Recessive hereditary disorder (autosomal)(parent)
Quick Facts
- SNOMED CT
- 190905008
- UMLS CUI
- C0010674
- Fully Specified Name
- Cystic fibrosis (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 30
- Known Treatments
- 10
- Clinical Trials
- 75
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.